and not used menopausal hormone therapy; (2) no serious medical condition that would prevent the participant from returning for her annual mammogram in 12 months, (3) not pregnant; (4) no history of cancer, including breast cancer; (5) and no history of breast augmentation or reduction. ...
cumulative absolute risk of breast cancer mortality over the ages 55–79 years for women in the United Kingdom, assuming that women who began screening at 50 years would gain no benefit in the first 5 years, but that the mortality reduction would continue for 10 years after screening ended....
Whilst meta-analysis of randomised clinical trial data clearly demonstrates a reduction in the relative risk of breast cancer mortality due to screening, reduced breast cancer deaths may come at the expense of overdiagnosis (the identification and unnecessary treatment of clinically insignificant tumours),...
Who participates in a randomized trial of mindfulness-based stress reduction (MBSR) after breast cancer? A study of factors associated with enrollment amon... BackgroundDiscussion regarding the necessity to identify patients with both the need and motivation for psychosocial intervention is ongoing. ...
Purpose/Objectives: To identify an appropriate theoretical framework to study exercise motivation for breast cancer risk reduction among high-risk women.Data Sources: An extensive review of the literature was conducted to gather relevant information pertaining to the Health Promotion Model, self-determinat...
(2 × 104cells/well) were seeded into 96-well plates. After 24 hours, 100 μl of medium containing 50 mM EdU was added to each well, and the cells were then incubated for 2 hours at 37 °C. The cells were then fixed with 4% paraformaldehyde and stained with Hoechst and Apollo ...
The keyhole pattern corresponds to the incision pattern generally utilized for the vertical short scar and the inferior pedicle techniques for breast reduction or mastopexy surgery and comprises a generally circular pattern and a generally linear pattern, with the generally linear pattern extending ...
Further work is required to clarify whether the response to neoadjuvant chemotherapy can be used to guide the selection of patients for regional nodal irradiation [207] or whether patients who are clinically node positive before neoadjuvant chemotherapy and are converted to node negative after neoadjuvan...
Models that recapitulate the complexity of human tumors are urgently needed to develop more effective cancer therapies. We report a bank of human patient-derived xenografts (PDXs) and matched organoid cultures from tumors that represent the greatest unmet need: endocrine-resistant, treatment-refractory ...
Methods: The expression of MYO10 and its associations with clinicopathological and biological factors were examined in breast cancer cells and breast cancer specimens (n ¼ 120). Cell migration and invasion were investigated after the silencing of MYO10. The ability of cells to form invadopodia ...