Breast cancer, the world’s most commonly diagnosed cancer, is a heterogeneous disease that demands appropriate diagnosis for better patient management. Thus, the understanding of the molecular mechanisms of tumor heterogeneity, as well as the characteri
Neoadjuvant Endocrine Therapy in Breast Cancer Upregulates the Cytotoxic Drug Pump ABCG2/BCRP, and May Lead to Resistance to Subsequent Chemotherapy Baxter, Diana E.Kim, BaekHanby, Andrew M.Verghese, Eldo T.Sims, Andrew H.Hughes, Thomas A. 481-488 Efficacy and Safety of Ixabepilone and ...
Sims “just [doesn’t] make milk,” she added. “I would see these women, and they just stick that baby on the boob, and I watched it. … I watched [this woman named Allison] breast-feed. We have three kids almost all identical in age and I was like, ‘I’m so sorry, Allison...
Liu GY, Moon SH, Jenkins CM, Li M, Sims HF, Guan S, et al. The phospholipase iPLA(2)gamma is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling. J Biol Chem. 2017;292(25):10672–84. Article CAS PubMed PubMed Cent...
Diana BaxterSt. James's University HospitalUKAndrew HanbySt. James's University HospitalUKEldo VergheseSt. James's University HospitalUKAndrew SimsSt. James's University HospitalUKThomas HughesSt. James's University HospitalUKEuropean Journal of Surgical Oncology...
Sims, R.B. Clarke Wnt pathway activity in breast cancer sub-types and stem-like cells PLoS One, 8 (7) (2013), Article e67811 CrossrefView in ScopusGoogle Scholar [64] C. Brisken, B. O’Malley Hormone action in the mammary gland Cold Spring Harb. Perspect. Biol., 2 (12) (2010)...
Compound1was isolated as colorless needle crystals. Its molecular formula, C35H42N6O6S4, was established by HRESIMS (m/z793.1934 [M + Na]+, calcd. 793.1941). Its IR spectrum showed characteristic absorptions of hydroxyl group (3399 cm−1) and four carbonyl groups (1605, 1632, 1647 an...
This is the first description of the structure 16β-formyloxy-5β,11α,14β-trihydroxy-3β,4β-epoxy-19-oxobufa-20,22-dienolide, named hellefoetin C. The molecular formula of 11 was established as C24H30O8 from the HRESIMS data (m/z 447.2009 [M+H]+, calcd for C24H31O8 ...
Neoadjuvant Endocrine Therapy in Breast Cancer Upregulates the Cytotoxic Drug Pump ABCG2/BCRP, and May Lead to Resistance to Subsequent Chemotherapy.doi:10.1016/j.ejso.2018.10.041Baek KimUniversity of LeedsEuropean Journal of Surgical Oncology
Saben, J.L.; Sims, C.R.; Abraham, A.; Bode, L.; Andres, A. Human milk oligosaccharide concentrations and infant intakes are associated with maternal overweight and obesity and predict infant growth. Nutrients 2021, 13, 446. [Google Scholar] [CrossRef] Oliveros, E.; Martin, M.; Torres...