Two women taking oral prednisone provided milk by complete breast emptying using a breast pump every 2 to 3 hours over one dosage interval. One subject was taking a dose of 2 mg every 12 hours and the other was taking 15 mg every 24 hours. The respective infant weight-adjusted dosages we...
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This indicates control/parental MDA-MB-231 cells can pump out limited Dox due to low expression of MDR-1/ABCB1 and MRP1/ABCC1. Similarly, Tariquidar pretreatment successfully reduced drug efflux in DEHP exposed clone #1 and 2 overexpressing MDR-1/ABCB1 and MRP1/ABCC1. Dox accumulation was ...