“That’s an important advancement because surgical biopsies have side effects and risks, despite having a low probability of a positive result confirming the presence of cancer cells,” Dogan explained. “Improving our ability to rule out axillary metastasis during a routine MR...
MRI (magnetic resonance imaging) is a technology that uses magnets and radio waves to create detailed, 3D images of the breast tissue. Before the test you may be injected with a contrast solution (dye) through an intravenous line in the arm. The contrast solution will allow potential cancerou...
Breast MRI MRI (magnetic resonance imaging) is a technology that uses magnets and radio waves to create detailed, 3D images of the breast tissue. Before the test you may be injected with a contrast solution (dye) through an intravenous line in the arm. The contrast solution will allow potent...
lymphoscintigraphy and blue dye mapping are commonly used to identify the SLNs during surgical treatment of breast cancer. In recent years, contrast-enhanced ultrasound (CEUS) using microbubble-based agents has investigated for evaluation of lymphatic system in both animal and human studies5,6. The...
In contrast, a dose-dependent increase in cytotoxicity was observed in the agent-treated cells (Fig. 8-I; rows A–E), in which the cells treated with HIDPPNPs and NIR laser irradiation (Fig. 8-I,E1–E6) underwent higher levels of cell death as compared to the cells treated with...
In contrast to SUM159 cells, SKBR3 breast cancer cells did not exhibit substantial changes in cytoskeletal dynamics or invasion in response to mechanical conditioning (Figures S5A–S5G). This correlates with their limited tumorigenicity and low metastatic potential in vivo (Holliday and Speirs, 2011...
Magnetic resonance imaging (MRI) is a very sensitive test that can find some tumors not detected by a mammogram (PDQ Screening Prevention Editorial Board 2017b). Women who are at especially high risk for breast cancer should get an MRI along with a mammogram every year (Mainiero 2017; Sardan...
Preclinical breast tumor models are an invaluable tool to systematically study tumor progression and treatment response, yet methods to non-invasively monitor the involved molecular and mechanistic properties under physiologically relevant conditions are
In contrast, in p140 cells, GM130 always localized in the inner part of the acini, oriented towards the lumen, while beta1 integrin was clearly restricted in the outer part of the acini, to define the basal compartment (Fig. 4i). Thus, at least under the conditions of in vitro assays...
MNPs have been utilized as nanocarriers for drugs, contrast imaging agents in magnetic resonance imaging (MRI), in local hyperthermia, and magnetic targeting.24,25 However, high aggregation of MNPs is a common problem. High surface-to-volume ratios and van der Waals forces trigger opsonization ...