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The overall aim of breast imaging can be summarized under several general headings. First, it is performed in symptomatic women to exclude breast cancer or other disease that requires immediate treatment. In this respect, it should provide a definitive diagnosis or exclude the presence of a harmful...
B Confocal imaging of paraffin sections of PIK3CAH1047R-iHBECCD117 cells in NOG mice costained for ALDH1A3 (green) and CALML5 (white; left), or keratin K23 (red) and CALML5 (white; right). Note that PIK3CAH1047R-iHBECCD117 expresses both ductal and lobular markers, albeit with a ...
The ability to measure biochemical and molecular processes underlies progress in breast cancer biology and treatment. These assays have traditionally been performed by analysis of cell culture or tissue samples. More recently, functional and molecular im
The limits of mammography have led to an increasing interest on possible alternatives such as the breast Computed Tomography (bCT). The common goal of all X-ray imaging techniques is to achieve the optimal contrast resolution, measured through the Contra
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Magnetic Resonance Imaging (MRI): MRI is used along with mammograms for screening women who have a high risk of developing breast cancer. It can also be used to examine suspicious areas found by a mammogram. Ultrasound: Breast ultrasound is used to target a specific area of concern found on...
Nectin-4-targeted immunoSPECT/CT imaging and photothermal therapy of triple-negative breast cancer Fuqiang Shao, Zhidi Pan, Yu Long, Ziyang Zhu, Kun Wang, Hao Ji, Ke Zhu, Wenyu Song, Yangmeihui Song, Xiangming Song, Yongkang Gai, Qingyao Liu, Chunxia Qin, Dawei Jiang...
The breast ductal and glandular system develops in the embryo from ectoderm that buds and invaginates into the mesenchyme (Fig. 3.1). Canalization of the central lactiferous ducts occurs near term birth. Until puberty the male and female breasts are anatomically similar. The cells of the breast...
Polarimetric guidance mapping was enabled by circular degree-of-polarization (DOP) imaging via both Stokes and Mueller matrix polarimetry. These results suggest a potential synergistic hybrid approach employing polarimetry as a wide-field-imaging guidance tool to optimize efficient probing of tissue ...