RABEX-5, a guanine nucleotide exchange factor (GEF) for RAB-5, plays an important role in cell mobility and altered expression associated with tumor metastasis. This study aimed to investigate the role of RABEX-5 in proliferation and metastasis of breast
Breast cysts usually do not need any treatment since they tendto disappear alone.Another type of breast lumps are fibroadenomas, which are solid and rubberygrowths that usually appear in the women’s 20s and 30s and which can be easilydetected since when they are touched, they can move very...
In adult women, particularly postmenopausal women, obesity is believed to increase breast cancer risk through multiple mechanisms, including increased inflammation, growth factor secretion (e.g., FGF1), and local estrogen synthesis as well as an imbalance of adipokines and diminished PPAR-γ activity...
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Estrogen promotes cell growth and progesterone causes cell maturation and stabilization. It is in the growth phase that cell undergoes malignant transformation, i.e. cancer formation occurs. Therefore, factors such as early menarche[start of menses], late menopause[stopping of menses], alcohol, ...
Breast cancer is the most common cancer in women and affects 1.38 million women worldwide per year. Antiestrogens such as tamoxifen, a selective estrogen receptor (ER) modulator, are widely used in clinics to treat ER-positive breast tumors. However, rem
A recent study has demonstrated that blockage of HMGA1 increases sensitivity to tamoxifen by inducing cell growth through reduced ERα46 expression in a tamoxifen-resistant BC cell line [15]. Our bioinformatic analyses from the same ER+ BC showed a significant increase in HMGA1 expression level....
Growth during milk production Your breasts are likely to increase significantly in size during pregnancy; your milk ducts are maturing and filling up with milk. While you nurse postpartum, your breasts will remain full, but as you stop nursing, your milk production cells will shrink as new fatt...
Long noncoding RNAs (lncRNAs) have surpassed the number of protein-coding genes, yet the majority have no known function. We previously discovered 844 lncRNAs that were genetically linked to breast cancer through genome-wide association studies (GWAS). H
removing hair from the affected area becomes necessary.Breast laser hair removal in Delhiis done in such a way that it reduces the growth of the hair to minimal. When compared to the electrolysis treatment, laser treatment is quite safer and offers positive results. Certainly, the breast can ...