Immediately, Kate Rackham began treatment for the metastatic breast cancer, which included a new chemotherapy regimen. For about four years, the treatment seemed to be slowing the cancer growth. But in April 2023, everything changed. “We had nothing but bad news,” Mark Rackham recalls. “...
Estrogen promotes cell growth and progesterone causes cell maturation and stabilization. It is in the growth phase that cell undergoes malignant transformation, i.e. cancer formation occurs. Therefore, factors such as early menarche[start of menses], late menopause[stopping of menses], alcohol, ...
A recent study provides a biologic underpinning for why risk is associated with each additional ovulatory cycle, where bouts of growth and regression drive the local and coordinated expansion and loss of mammary stem cells. While there are protective mechanisms to eliminate mutant clones that arise,...
I got worried about it one day when I went to take off my bra and noticed that my left breast was sort of folded in half inside the cup, with the nipple sunken in the middle. This seemed distinctly not good, so I nervously did a self-exam and visual inspection. This time, I notic...
Evaluation of adipogenesis over time using a novel bioabsorbable implant without the addition of exogenous cells or growth factors 2024, Regenerative Therapy Citation Excerpt : Standard treatments include autologous composite tissue reconstruction, silicone implants, and autologous fat grafting. However, these...
It stands for “Human Epidermal Growth Factor Receptor 2”, which is a protein that is believed to indicate the aggressiveness of breast cancer. Herceptin is one of the current medicines recommended to prevent recurrence or metastasis of Her2Neu-positive breast cancers. The five-year disease-free...
Platycodin D (PD), the primary active component of PG, has been reported to inhibit the growth of various tumors, including glioma, oral cancer, breast cancer, gastric cancer, non-small cell lung cancer, liver cancer, leukemia melanoma and bladder cancer [21, 22]. From a mechanistic ...
Growth during milk production Your breasts are likely to increase significantly in size during pregnancy; your milk ducts are maturing and filling up with milk. While you nurse postpartum, your breasts will remain full, but as you stop nursing, your milk production cells will shrink as new fatt...
Multivorum accelerated tumor growth in vivo Given that S. multivorum was one of the most abundant bacteria residing in tumor tissues of breast cancer patients, we hypothesized that S. multivorum may promote breast cancer progression. Using the 4T1 tumor-bearing mouse model, we investigated the ...
Although pregnancy and the diagnosis of breast cancer are occasionally concurrent, it is a more likely scenario that many of these patients have had an unknown subclinical breast cancer while pregnant, given that the occult preclinical breast cancer growth time is several years.53 This issue has ...