Invasive breast cancer (BrCa) is predicted to affect 1 in 9 women in a lifetime;1 in 32 will die from this disease. The most aggressive forms of BrCa, basal-like/triple-negative phenotype (TNBC), are challenging to treat and result in higher mortality du
Introduction to the Diagnosis of Diseases of the BreastFrederick C. Koerner MDDiagnostic Problems in Breast Pathology
A proportion of the remaining familial breast cancer risk is explained by common low penetrance alleles, of which the majority that have been studied are single nucleotide polymorphisms (SNPs). Carriage of the risk allele at these loci typically confers between a 1.04-fold to 1.40-fold increase o...
Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA Gamal Mostafa MD (Attending Surgeon), Lamont Cathey MD (Resident) & Frederick L. Greene MD (Chairman) (Attending Surgeon), (Resident) & (Chairman)
Levy, MD: We’re going to shift gears. The breast [cancer] team is going to be front and center first here because ADCs [antibody–drug conjugates] have landed in breast cancer first. Once again, we’re trying to learn about ADCs from breast cancer because you guys have had a lot of...
WL Farrar, (NCI-Frederick Cancer Research and Development Center, Frederick, MD, USA). Each of the above plasmids (1 mg) were transfected with Lipofectamine 2000 (Invitrogen) in co-transfection with a thymidine kinase promoter driven Renilla luciferase (40 ng) plasmid as a reference control (...
Six-week-old, specific pathogen-free athymic NCr-nu/nu mice were purchased from Charles Rivers or from the Animal Production Area of the National Cancer Institute-Frederick Cancer Research and Development Center (Frederick, MD). The care and use of laboratory animals was in accordance with the ...
Laboratory of Cancer Immunometabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA Veena Somasundaram & David A. Wink Contributions MF designed the experiments, performed most of the experimental works, data analysis, and prepared the manuscrip...
Cancer Center, Sanford-Burnham Medical Research Institute, 10901, North Torrey Pines Road, La Jolla, CA, 92037, USA Marcia I Dawson Corresponding author Correspondence to Eduardo F Farias. Additional information Competing interests The authors declare that they have no competing interests. Authors' con...
Maternal and Child Wellbeing Unit, African Population and Health Research Center, Nairobi, Kenya Frederick Murunga Wekesah, Milka Njeri Wanjohi, Peter Muriuki & Elizabeth W. Kimani-Murage Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrec...