Breast Carcinoma: this chapter outlines the incidence, risk factors, clinical presentation, investigations, treatments and prognosis of cancer at this anatomical site. These features are correlated with the core data that are required to make the corresponding histopathology reports of a consistently high...
Hematoxylin-eosin staining was used to analyze the original tumor tissue and carcinoid organ sections to determine whether the breast carcinoid organs matched the histological type of the original tumor, such as invasive ductal carcinoma or invasive lobular carcinoma. The staining revealed typical malignan...
The second most common type is Infiltrating Lobular Carcinoma (ILC). Cancer starts in the lobules or the lobes and spreads the body. ILC usually responds well to hormone therapy. There are other types of BC which are seen less. Male breast cancer is incredibly rare and it is always ductal...
pertuzumab mediates ADCC similar to trastuzumab7. Results to date suggest that engagement of HER2 at multiple epitopes confers clinical benefit. As such, pertuzumab is given in combination
Approved antibody-drug conjugates (ADCs) for HER2-positive breast cancer include trastuzumab emtansine and trastuzumab deruxtecan. To develop a differentiated HER2 ADC, we chose an antibody that does not compete with trastuzumab or pertuzumab for binding
For BrC classification, mass spectrometry imaging is not employed with deep learning, although it did enable precise classification of distinct-type carcinomas. These imaging technologies need to be investigated in BrC classification. Multi-modality research must be investigated. Sutdies have also ...
In this study of 94 early-stage breast carcinomas, we observed a general agreement of r2 = 0.79 between ROR assessed from macrodissected FFPE tumor tissue and ROR from fresh-frozen bulk tumor tissue. Overall, we observed a higher proportion of the normal-like subtype using RNA extracted from...
CarcinomaAdvance and New Insights in Bladder CancerAdvance in Colorectal Cancer: A Themed Issue in Honor of Prof. Bengt GlimeliusAdvance in Computational Methods in Cancer ResearchAdvance in Hepatopancretobiliary Cancers: A Themed Issue in Honor of Prof. Dr. Timothy M. PawlikAdvanced Neuroendocrine ...