“For the first time, our research has shown that without RAC1B, breast cancer stem cells can’t form tumours and become more vulnerable to chemotherapy, making the treatment even more effective. Positively RAC1B isn’t needed for healthy cells so targeting RAC1B...
Little is known about the relationships between breast cancer treatments, costs,and outcomes across different population groups, health care delivery settings, and geographic areas. As a result of this uncertainty the cost effectiveness of different patterns of breast cancer prevention and treatment ...
Targeting cancer stem cells (CSCs) has great potential in anti-cancer treatment. Here this group reports the role of antibiotic Nifuroxazide as a potent anti-CSC compound and fabricates it into an anti-breast CSC prodrug using click chemistry strategy. Celia D. Rouault , Lucile Bansard & Christ...
Aromatase inhibitors are used to treat some types of breast cancer or to keep it from coming back. They may also be used to help prevent breast cancer in some women who are at a high risk of developing it. These medications block the activity of an enzyme called aromatase, which the body...
In breast cancer treatment, 5-FU is often combined with other chemotherapy drugs to maximize its effectiveness17. It may be given before surgery as a neoadjuvant therapy to reduce the tumor burden, or it can be administered as a post-surgical treatment to target any residual malignancy and ...
It is an additive that enhances the effectiveness of medical treatment. (Figure 4: Adjuvant) agent Br['eɪdʒ(ə)nt]Am['edʒənt] 剂 A chemical that has a particular effect or is used for a particular purpose...
Metformin is in clinical trial as an adjuvant for breast cancer treatment and demonstration of effectiveness in this situation could lead to assessment for prevention including in prediabetic populations [75]. Molecular pathology Current status Breast cancer classification and issues of heterogeneity During...
"If our work translates into the clinic," said Coussens, "it may improve the effectiveness of chemotherapy in the treatment of certain cancers." A research article describing this discovery appears in the inaugural issue of the journal Cancer Discovery today. Coussens also is presenting the results...
Therefore, with the purpose of exploring new targets for drugs of breast cancer treatment, predicting new drug–target interactions (DTIs) is a good solution. The cost and time factors associated with the development of new drugs on a commercial scale [5,6,7] warrant the need for examining ...
In summary, several delivery methods, such as nano-micelles, nanocomposites, and pH-sensitive nanocarriers, have been developed to enhance the effectiveness of curcumin. Promising results in studies on breast cancer cells indicate that curcumin can increase cytotoxicity and induce apoptosis. ...