Sprague, PhD; for the Population-based Research Optimizing Screening Through Personalized Regimen (PROSPR) Consortium JAMA Oncology Key Points Question What is the invasive breast cancer detection rate of abbreviated breast magnetic resonance imaging (MRI) compared with digital breast tomosynthesis (DBT) ...
On the basis of the predictive prognostic nomograms, a network survival rate calculator was developed for individualized survival prediction in patients with mTNBC. Results: A total of 2230 patients diagnosed with mTNBC were included in the Surveillance, Epidemiology, and End Results database for ...
pCR was defined as the absence of residual invasive cancer cells in the breast and axillary lymph nodes (ypT0/is +ypN0).10 Residual cancer burden (RCB) index was calculated using the web-based calculator (available on internet),25 by considering dimensions of the primary tumour, tumour bed ...
pathway activity induced by gedatolisib versus single-node PAM inhibitors also resulted in greater inhibition of PAM-controlled functions, such as protein synthesis, cell cycle and DNA replication, cell migration and invasion, and metabolic activities required for cancer cell survival and proliferation...
Since the late 1970s, tremendous progress has been achieved in the understanding and management of breast cancer. However, locally advanced breast can- cer (LABC) remains a difficult clinical challenge, with a long-term survival rate of less than 50% 1. Treatment of LA...
Disease-free and overall survival were defined from the date of diagnosis. The residual cancer burden index was calculated using an online calculator.31,32 Patients underwent standardized evaluations before surgery and then at 3, 6, 12, 18, and 24 months after RT. These evaluations included ...
complete response rate of 2%, partial response rate of 78%, stable disease rate of 15%, progressive disease rate of 5%, responsiveness rate of 80%, and nonresponsiveness rate of 20%. According to the data, the majority of the breast cancer patients who underwent chemotherapy had a partial ...
Uberall, I.et al. Tumor Autophagy is Associated with Survival Outcomes in Patients with Resected Non-Small Cell Lung Cancer.Lung Cancer.129, 85–91 (2019). ArticleGoogle Scholar Takeuchi, M.et al. Perioperative Risk Calculator for Distal Gastrectomy Predicts Overall Survival in Patients with Gastr...
Breast cancer is the most commonly diagnosed neoplasm in women worldwide with a well-recognized heterogeneous pathology, classified into four molecular subtypes: Luminal A, Luminal B, HER2-enriched and Basal-like, each one with different biological and clinical characteristics. Long non-coding RNAs (...
Advances in management of early-stage breast cancer include increasing use of neoadjuvant (presurgery) systemic therapy and oncoplastic surgical techniques in selected patients and the availability of new systemic therapies. These include targeted monoclonal antibody therapies, cyclin-dependent kinase 4/6 ...