KP receives research support and is a consultant to Novartis Pharmaceuticals, Inc.; KP is also a member of the scientific advisory boards of Metamark Genetics Inc., and Theracrine Inc., and owns stocks of Aveo Pharmaceuticals Inc. Andrew E Place, Sung Jin Huh contributed equally to this work...
Worldwide, many patients with HER2+ (human epidermal growth factor receptor 2-positive) early breast cancer (BC) do not receive adjuvant trastuzumab. Hazards of recurrence of these patients with respect to hormone receptor status of the primary tumor have not been described. Methods Using data fro...
Recent data indicate that receptor for activated C kinase 1 (RACK1) is a putative prognostic marker and drug target in breast cancer (BC). High RACK1 expression is negatively associated with overall survival, as it seems to promote BC progression. In tum
data interpretation, and decision to submit for publication in conjunction with the authors. Research support in the form of medical writing assistance, furnished by Sunaina Indermun, PhD, and Brian Law, PhD, of Nucleus Global, an Inizio company...
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2. Breast cancer research model 2.1. Two-dimensional cell model The traditional approach to culturing cells in two dimensions is a widely adopted technique that involves growing single cells or cell populations in a flat surface, attempting to simulate an in vivo environment in vitro (Fig. 1A)....
Biochemical & Biophysical Research CommunicationsKlotz DM, Castles CG, Fuqua SAW, Spriggs LL, Hill SM (1995) Differential expression of wild-type and variant ER mRNAs by stocks of MCF-7 breast cancer cells may account for differences in estrogen-responsiveness. Biochem Biophys Res Comm 210: 609...
- 《Cancer Research》 被引量: 2914发表: 2007年 Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. As trials of 5 years of tamoxifen in early breast cancer mature, the relevance of hormone ...
Re: Corporations flock to selling for the (breast cancer) cure. Re: Corporations flock to selling for the (breast cancer) cure.errorshealth insurance payorsComment in J Natl Cancer Inst. 2005 Feb 16;97(4):320... Susan,Braun - 《Journal of the National Cancer Institute》 被引量: 53发表...
Cancer-testis antigens (CTAGs) are expressed solely in germ cells and in malignant tissues. They are targets of immune responses mediated by cytotoxic T cells in some cancers, and there is much interest in developing vaccines that induce these responses.