Breast cancer is one of the most common cancers in women and is closely associated with obesity. Gremlin-2 (GREM2), an antagonist for bone morphogenetic proteins (BMPs), has been considered an inhibitor of adipogenic differentiation in adipose-derived stromal/stem cells. However, the role of ...
The pubertal/early adult life stage is particularly important because it represents one of the critical “windows of susceptibility” to breast cancer. During puberty, under the influence of estrogen, MECs proliferate at an exponential rate yet remain incompletely differentiated; the result is an accum...
Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association analysis with in silico genomic featu
There is a support group for breast cancer patients who volunteer to help those recently diagnosed, and you can be matched with a volunteer who has the same type of breast cancer. “Can you at least pair me up with someone with the volunteer support group?” I asked Pamela. “No,” Pam...
On Sunday in church, we read Psalm 88 together. A chapter where there is just a continual crying out to God with no real answer. The sixth and seventh verses jumped out at me. “You have put me in the lowest pit, in dark places, in the depths. Your wrath has rested upon me, and...
Our objectives and scope are: to develop a competitive and successful breast cancer research program that focuses in cancer control and population sciences at UTPA; to develop and complete a research project on barriers to breast cancer screening among Latinas in the U.S.-Mexico border region; ...
Mono-allelic germline pathogenic variants in the Partner And Localizer of BRCA2 (PALB2) gene predispose to a high-risk of breast cancer development, consistent with the role of PALB2 in homologous recombination (HR) DNA repair. Here, we sought to define
This guideline updates the American Cancer Society breast cancer screening recommendations for women at average risk for breast cancer.
Coping With Breast Cancer Together; Shared Disease Bonds Women at Silver Spring Church Series: IN THE SHADOW OF BREAST CANCER: AN EMERGING SISTERHOOD Series Number: 2/2Amy Goldstein
Breast cancer research and therapy has been greatly improved over the last decades. Nevertheless, statistical data from 2020 reports that almost 2.3 million new cases of breast cancer were diagnosed and that more than 680.000 people succumbed to the disease, making this the most diagnosed cancer wor...