New drug prevents breast cancerPresents questions relating to the drug tamoxifen being used for the prevention of breast cancer. Details on the effectiveness of the drug; Information on who will benefit most from this drug; Reference to the side...
A drug that canhalve the riskof developing breast cancer in post-menopausal women has been approved for use in the UK. This drug, called anastrozole, could benefit an estimated 289,000 women in the UK who are atincreased risk of breast cancer. Anastrozole was already approved for use in th...
They are often used with other cancer drugs for early and locally advanced tumors, metastatic disease, and in neoadjuvant treatment before surgery. These medications are given by injection or orally. HER2 therapy is not used for HER2 negative breast cancer. Side effects vary by drug given, but ...
Tamoxifen:Tamoxifen is the first SERM to receive approval from the United States Food and Drug Administration (FDA) in the treatment of breast cancer. Some breast cancer cells are "estrogen sensitive," meaning they possess so-called estrogen receptors and need estrogen to grow and divide. But es...
Combination of Breast Cancer Prevention with Tissue-Targeted Hormone Replacement Therapy LABRIE F: Drug insight: breast cancer prevention and tissue-targeted hormone replacement therapy. Nat Clin Pract Endocrinol Metab 3: 584-593, 2007... F Labrie 被引量: 119发表: 2008年 Drug insight: Testosterone...
Tamoxifen was approved for breast cancer prevention in October 1998. Thus, for the first time, we as gynecologists are being asked to prescribe this drug to healthy women. In the past each one of us has cared for women with breast cancer who have been treated with tamoxifen by oncologists ...
Drug Des. Devel Ther. 9, 4479–4499 (2015). CAS Google Scholar Shull, J. D., Dennison, K. L., Chack, A. C. & Trentham-Dietz, A. Rat models of 17beta-estradiol-induced mammary cancer reveal novel insights into breast cancer etiology and prevention. Physiol. Genomics 50, 215–234...
Prevention of breast cancer is still under clinical investigation with only one drug, tamoxifen, showing benefit in high risk patients. This paper reviews the possible sites for prevention of neoplastic transformation via biomarkers in a breast cell as well as the investigational drugs and their ...
Wong, MD JAMA JAMA Patient Page Patient Information: Breast Cancer Risk–Reducing Medications Danielle Graham, MD, MBA; Maggie L. DiNome, MD; Patricia A. Ganz, MD JAMA Podcast (31:43) Drug Treatment for Primary Prevention of Breast Cancer 1x 0:00 / 0:00 Subscribe to Podcast ...
Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study BACKGROUND: The finding of a decrease in contralateral breast cancer incidence following tamoxifen administration for adjuvant therapy led to the concept that the drug might play a ...