Tumor-derived miR-9-5p-loaded EVs regulate cholesterol homeostasis to promote breast cancer liver metastasis in mice Tumor-derived extracellular vesicles (EVs) critically regulate tumor development and progression. Here the authors show that, in a mouse model of breast cancer, miR-9-5p-loaded EVs...
Research articles should report on original primary research. Breast Cancer Research strongly encourages that all datasets on which the conclusions of the article rely should be available to readers. We encourage authors to ensure that their datasets are either deposited in publicly available repositories...
Breast cancer starts as a local disease, but it can metastasize to the lymph nodes and distant organs. At primary diagnosis, prognostic markers are used to assess whether the transition to systemic disease is likely to have occurred. The prevailing model
Early life environmental exposures affect breast development and breast cancer risk in adulthood. The breast is particularly vulnerable during puberty when mammary epithelial cells proliferate exponentially. In overweight/obese (OB) women, inflammation increases breast aromatase expression and estrogen synthesis...
Breast cancer is one of the leading cause of mortality and morbidity in Canada. Screening is the most promising approach in identification and treatment of the disease at early stage of its development. Research shows higher rate of breast cancer mortali
Clinical Breast Canceris a peer-reviewed journal that publishes original articles describing various aspects of clinical and translational research ofbreast cancer. Publishing eight issues per year,Clinical Breast Canceris devoted to articles ondetection,diagnosis,prevention, andtreatment… ...
This guideline updates the American Cancer Society breast cancer screening recommendations for women at average risk for breast cancer.
National Cancer Institute. 2022. Accessed March 26, 2024. https://seer.cancer.gov/data-software/documentation/seerstat/nov2021/ 4. Henderson JT, Webber EM, Weyrich M, Miller M, Melnikow J. Screening for Breast Cancer: A Comparative Effectiveness Review for the US ...
More on Breast Cancer Types and Growth Breast Cancer Growth and Screening 5 min read If you or someone you know has breast cancer, you may wonder how fast the cancer is growing. You might also wonder how fast it will continue to grow. Doctors don’t have a way to know when your can...
The tumour immune microenvironment is shaped by the crosstalk between cancer cells, immune cells, fibroblasts, endothelial cells and other stromal components. Although the immune tumour microenvironment (TME) serves as a source of therapeutic targets, it is also considered a friend or foe to tumour-...