GenomicsLymph nodeBreast cancerClinical observations about lack of survival benefit after extensive axillary surgery and biological discordance between primary breast tumors and axillary lymph nodes raise the question of the actual metastatic potential of axillary nodal disease. The exploration of intratumoral...
Axillary lymph node dissection for T1a breast carcinoma: is it indicated?Cancer 1994;73:664–7. CAS PubMed Google Scholar Reger V, Beito G, Jolly PC. Factors affecting the incidence of lymph node metastases in small cancers of the breast.Am J Surg 1989;157:501–2. Article CAS PubMed ...
B: Enlargement of tumor-involved lymph node is seen with the invasion and growth of cancer cells. B cells accumulate in tumor-involved lymph nodes (germinal centers are depicted as darker blue), whereas the overall T cell compartment contracts. Of note, the regulatory T cell population has ...
Tumor draining lymph nodes connected to cold triple-negative breast cancers are characterized by Th2-associated microenvironment Triple-negative breast cancers are aggressive tumours, but their prognosis is critically determined by the immune cell activity within the microenvironment, with the more inflamed...
Tumor-draining lymph node (TDLN) invasion by metastatic cells in breast cancer correlates with poor prognosis and is associated with local immunosuppression, which can be partly mediated by regulatory T cells (Tregs). Here, we study Tregs from matched tu
Molecular Cancer BioMed Central Research Open Access Lymphangiogenesis and lymph node metastasis in breast cancer Giles H Cunnick1, Wen G Jiang1, Tony Douglas-Jones2, Gareth Watkins1, Kelvin F Gomez1, Mike J Morgan2, Ashok Subramanian*3, Kefah Mokbel3 and Robert E Mansel1...
The combination of the two factors is most meaningful in patients with 1 to 3 positive nodes. 展开 关键词: Breast cancer Lymph nodes Lymphovascular invasion Prognosis DOI: 10.1016/S0002-9610(02)00950-9 年份: 2002 收藏 引用 批量引用 报错 分享 ...
Intraoperative lymphatic mapping and sentinel lymph node dissection in breast cancer Because the tumor status of the regional lymph nodes is the most important prognostic factor in patients with early-stage breast cancer, accurate histopath... EC Hsueh,N Hansen,AE Giuliano - 《Ca A Cancer Journal...
lymph node metastasis of breast cancer, we show that primary tumors induced B cell accumulation in draining lymph nodes. These B cells selectively promoted lymph node metastasis by producing pathogenic IgG that targeted glycosylated membrane protein HSPA4, and activated the HSPA4-binding protein ITGB...
ONLINE FIRST: Lymph Node Status Losing Importance in Breast Cancer?StockwellSerena