The prognosis of breast cancer in elderly patients is often uncertain in consequence of higher co-morbidity. Earlier studies proved that the Nottingham Prognostic Index (NPI) -taking account tumour size, grade and lymph node involvement - correlates with the occurrence of later metastases and overall...
Objective: To explore the correlation between the clinical pathologies of breast cancer in the elderly and youths as well as their prognosis. Methods:Two hundred and eighty breast cancer patients were divided into a youth group (<60, n=120) and an elderly group (≥60, n=160) according to ...
Although the prognosis of breast cancer patients has generally improved during the last few decades, there is still a demand for evidence-based optimization of therapeutic interventions in older patients. 展开 关键词: Aged Breast Disease management Neoplasms Therapeutics ...
Breast cancer is the most prevalent kind of cancer among women and there is a need for a reliable algorithm to predict its prognosis. Previous studies focused on using gene expression data to build predictive models. However, recent advancements have made multi-omics cancer data sets (gene expres...
The objective of this study was to assess the impact of pre-existing diabetes on breast cancer prognosis. Women (n=2833) with centrally confirmed invasive breast cancer in the Women's Health Initiative, who were linked to Medicare claims data (CMS) were followed from the date of breast cancer...
Breast-conserving surgery followed by radiotherapy is part of standard treatment for early-stage breast cancer. Hypoxia is common in cancer and may affect the benefit of radiotherapy. Cells adapt to hypoxic stress largely via the transcriptional activity
Introduction A genetic component is well established in the etiology of breast cancer. It is not well known, however, whether genetic traits also influence prognostic features of the malignant phenotype. Methods We carried out a population-based cohort
Cancer screening in elderly patients: a framework for individualized decision making. JAMA. 2001;285(21):2750-2756. Table 1. Interpretation of Strong and Qualified Recommendations by Users of the Guidelinea View LargeDownload Table 2. Critical and Important Outcomes of Screening Mammography and ...
To compare RCB (Residual Cancer Burden) and Neo-Bioscore in terms of prognostic performance and see if adding pathological variables improve these scores. Methods We analysed 750 female patients with invasive breast cancer (BC) treated with neoadjuvant chemotherapy (NAC) at Institut Curie between 200...
Later on, the colorectal, breast and prostate cancer cases recruited in the case–control phase were incepted in three cancer-specific cohorts in order to ascertain clinical, genetic and epidemiological factors associated with prognosis17. From here on, we only refer to the breast cancer cohort. ...