Breast cancer immunotherapy: Facts and hopes. Clin. Cancer Res. 24, 511–520. https://doi.org/10.1158/1078-0432.CCR-16-3001 (2018). Article CAS PubMed Google Scholar Vranic, S., Cyprian, F. S., Gatalica, Z. & Palazzo, J. PD-L1 status in breast cancer: Current view and ...
Emens LA. Breast cancer immunotherapy: facts and hopes. Clin Cancer Res. 2018;24(3):511–20. Article CAS Google Scholar Meric-Bernstam F, Larkin J, Tabernero J, Bonini C. Enhancing anti-tumour efficacy with immunotherapy combinations. Lancet. 2021;397(10278):1010–22. Article CAS Google...
The cancer-immunity cycle coined by Chen et al. elegantly describes events needed to drive effective antitumor immunity [Citation19]. As tumor cells are recognized and destroyed, antigen-presenting cells (APCs), such as dendritic cells (DCs), acquire and present tumor antigens to nearby T-cells...
Emens LA. Breast cancer immunotherapy: facts and hopes. Clin Cancer Res. 2018;24(3):511–20. https://doi.org/10.1158/1078-0432.CCR-16-3001. Article CAS PubMed Google Scholar Youlden DR, Cramb SM, Yip CH, Baade PD. Incidence and mortality of female breast cancer in the Asia-Pacific...
Functional analysis demonstrated enrichment of CCNB2 co-expressed genes with the cell cycle, cancer progression, cell energy, and immune pathways. Microsatellite instability and tumor mutation burden analyses indicated CCNB2 as a candidate immunotherapy target. Tumor-infiltrating myeloid-derived suppressor ...
Immunotherapy for Triple-Negative Breast Cancer.The experimental monoclonal antibody MPDL3280A extended progression-free survival and produced durable responses in some patients with triple-negative breast cancer, according to preliminary results from a phase I trial.Alvaro MorenoAspitia...
The development of immunotherapy agents has revolutionized the field of oncology. The only FDA-approved immunotherapeutic approach in breast cancer consists of immune checkpoint inhibitors, yet several novel immune-modulatory strategies are being activel
Summary and Quick Facts for Breast Cancer Breast cancer is the second most common cancer among American women, behind skin cancer. About 250,000 women in the United States are diagnosed each year. In this protocol, you will first learn how breast cancer is typically detected and treated. Nex...
Breast Cancer Immunotherapy: Facts and Hopes. Immunotherapy is revolutionizing the management of multiple solid tumors, and early data have revealed the clinical activity of programmed cell death-1/programmed death ligand-1 (P... 查看全部>> LA Emens - Clin Cancer Res 被引量: 0发表: 2017年 Bre...
Breast cancer (BC) is a complex disease with profound genomic aberrations. However, the underlying molecular disparity influenced by age and ethnicity remains elusive. In this study, we aimed to investigate the molecular properties of 843 primary and met