28, 637–645 (2022). Article CAS PubMed Google Scholar Perez, E. A. et al. Safety and efficacy of vinorelbine in combination with pertuzumab and trastuzumab for first-line treatment of patients with HER2-positive locally advanced or metastatic breast cancer: VELVET Cohort 1 final results. B...
FDA Grants Accelerated Approval to Tucatinib Combination for Patients with HER2-Positive Metastatic Colorectal Cancer Erin Hunter, Assistant Editor January 20th 2023 This is the first indication for tucatinib that extends beyond the treatment of advanced unresectable or metastatic HER2-positive breast cancer...
2022. Accessed March 26, 2024. https://seer.cancer.gov/data-software/documentation/seerstat/nov2021/ 4. Henderson JT, Webber EM, Weyrich M, Miller M, Melnikow J. Screening for Breast Cancer: A Comparative Effectiveness Review for the US Preventive Services Task Force. ...
2. Current landscape of therapeutic vaccines for breast cancer 3. Vaccines targeting HER2 in breast cancer 4. Vaccines targeting triple-negative breast cancer 5. Vaccines targeting HR-positive breast cancer 6. Vaccines targeting breast cancer irrespective of the biological subtype 7. Other targets for...
A review of ~12,000 patients with breast cancer enrolled in randomized controlled trials evaluating trastuzumab alone or in combination with chemotherapy versus no treatment or standard chemotherapy alone as adjuvant therapy for breast cancer. Google Scholar Nahta, R. & Esteva, F. J. Herceptin: ...
BMI has also been demonstrated as an independent prognostic factor for overall survival (OS) in patients with early breast cancer (EBC) [[6], [7], [8]] [[6], [7], [8]] [[6], [7], [8]]. However, recent studies question the association between BMI and survival in EBC in ...
How have the updated NCCN guidelines influenced your practice for patients with HER2-positive breast cancer? The NCCN guidelines are important in guiding clinicians regarding best available evidence to support our treatment decisions. It’s very helpful to have guidelines that are ...
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Fig. 2: a) Progression-free survival and b) overall survival according to initial systemic anti-metastatic therapy of patients with hormone receptor-positive metastatic breast cancer. CI confidence interval, PFS progression-free survival, OS overall. ...
TRIB3 is associated with the stemness of breast cancer We queried the Curtis breast dataset from the Oncomine database of BCCs for information on 1556 patients with invasive ductal breast cancer and 148 patients with invasive lobular breast cancer. These patients expressed higher levels ofTRIB3than...