Final pathology revealed ductal carcinoma in situ (DCIS) in 7 % (6/89) and invasive cancer in 22 % (20/89). Microscopically clear margins were obtained in 55 % (11/20) of patients with invasive cancer. Of these, 82 % (9/11) chose not to undergo further local surgical therapy. Eigh...
The cancer team at Nature Communication have curated a research collection on the occasion of Breast Awareness Month in October, covering a variety of both translational and clinical research articles.
The COVID-19 pandemic significantly impacted breast cancer (BC) surgeries. Most studies showing reduced BC surgical volumes during the pandemic are from si
BC therapeutic vaccines [including peptide-based vaccines, protein-based vaccines, nucleic acid-based vaccines (DNA/RNA vaccines), bacterial/viral-based vaccines, and different immune cell-based vaccines] have emerged as an appealing class of cancer immunotherapeutics when used alone or combined with ...
Sentinel lymph node biopsy (SLNB), a standard surgical procedure for clinically axillary-negative breast cancer patients, significantly reduces complicatio
‘invasive’ describes the cancer’s main feature of spreading to other surrounding breast tissues. The condition starts at the milk ducts, which carries the milk from the lobules to the nipples, and then breaks the wall of the milk tubes and invade the other breast’s tissues. The ICD ...
This was followed by a stabilization or decline of trends in the early 2000s [17], likely a consequence of reduced use of menopausal hormone-replacement therapy and possibly a plateau in the detection of precancerous lesions/DCIS [18,19]. Rising incidence rates have been reported in several ...
Case-patient participants were women aged 20–49 years who were diagnosed with a first primary invasive breast cancer (ICD-O codes: C50.0–C50.9) between February 1998 and May 2003 (n = 1794; 1585 white and 209 African-American women). Control participants were women ages 20–49 years...
Learn more about this topic: Breast Cancer: Screening, Diagnosis, Treatment & Prognosis from Chapter 18 / Lesson 16 4.9K Breast cancer can be diagnosed early using several methods. Learn how to screen and diagnose breast cancer, the treatment options, and the important prognostic indicators. ...
Ductal carcinoma in situ (DCIS) is a potential precursor of invasive breast cancer (IBC). However, the natural course of a particular DCIS lesion is unknown, because almost all women with DCIS are treated. Furthermore, most studies are biased because these comprise DCIS adjacent to IBC, also...