Chemotherapy drugs used to treat earlybreast cancerinclude: Anthracyclines: This class of drugs includes doxorubicin (Adriamycin) and epirubicin (Ellence). Taxanes: This class of drugs includes docetaxel (Taxotere) and paclitaxel (Taxol). These drugs are often used with others like carboplatin (Parapl...
Many women presenting with Stage 11 or III breast cancer will relapse following initial adjuvant therapy. As current standard therapy will not cure patients with metastatic disease, dose intensification and new cytotoxic agents are being studied extensively. These new agents include vinorelbine, ...
Drugs used after and in addition to surgery are calledadjuvant therapy(辅助治疗). Chemotherapy or other types of therapy prior to surgery are calledneoadjuvant therapy(新辅助治疗). There are currently three main groups of medica...
Gene therapy for breast cancer initially involves local or systemic delivery. Local delivery may be intrapleural or via direct injection to lesions. However, systemic delivery remains the greatest challenge with targeting, although methods using antibodies or growth factor receptor ligands have been demon...
Chemotherapy Drugs Many drugs are used to fight breast cancer. The most common ones for neoadjuvant and adjuvant therapy are:2 5-fluorouracil (5-FU) Anthracyclines, includingAdriamycin(doxorubicin) and Ellence (epirubicin) Cytoxan (cyclophosphamide) ...
Mortality from breast cancer is almost exclusively a result of tumor metastasis and resistance to therapy and therefore understanding the underlying mechanisms is an urgent challenge. Chemotherapy, routinely used to treat breast cancer, induces extensive
JAMA.1980;243(17):1739-1741. doi:10.1001/jama.1980.03300430041021 FullText Abstract An analysis of 29 chemotherapeutic trials in 18 male patients with advanced breast cancer disclosed an overall response rate of 44%. Most of these chemotherapeutic trials consisted of single-agent regimens, namely, ...
Chemotherapy for Breast Cancer Carries a Small, but Concerning, Risk for LeukemiaCaroline Helwick
Obesity has been reported as an adverse prognostic factor in breast cancer, but inconsistently, and under-treatment with chemotherapy may occur. We provide the first assessment of obesity and breast cancer outcomes in a population-based, multi-ethnic cohort of New Zealand patients treated with chemot...
This article reviews the status of chemotherapy in the treatment of recurrent breast cancer with emphasis on single drugs, combination agent regimens, and combined modality approaches.Access through your organization Check access to the full text by signing in through your organization. Access through...