Chemo Protocol Shows No Benefit for Breast Cancer.Reveals that a high-dose chemotherapy for the treatment of metastic breast cancer is no more effective than conventional-dose chemotherapy. Comparison of three-year survival rate.ZolotJoanSolomon...
What Stages of Breast Cancer Does TC Chemo Treat? The TC chemotherapy combo is generally given in situations where a breast cancer tumor has been surgically removed and the cancer has notspread to lymph nodesormetastasized(spread to other areas of the body, such as the lungs, liver, or bones...
protocol components, such as (1) cell isolation and in vitro media formation, (2) cell incubation with various drugs, (3) cell survival assessment, and (4) interpretation of results. These are related to the recommendations of the National Comprehensive Cancer Network, American Society ofClinical...
An innovative MoS2 nanosheet system for combination therapy (PTT-chemo) of BC was reported by Cai et al. In this study, DOX was loaded onto the PDA-coated nanosheets. To create the resultant product, i.e., DOX@Apt-PEG-PDA-MoS2 nanosheets, the researchers modified the MoS2 nanosheets using...
Post-neoadjuvant treatment options for patients with triple-negative breast cancer (TNBC) include the chemo-drug capecitabine but also immune checkpoint inhibitors. Here the authors report the results of a phase II study of adjuvant nivolumab, capecitabine or the combination in patients with residual ...
(NCT02591966). All patients were diagnosed with histologically confirmed invasive breast cancer and treated at SMC. Patients were treated with a standard neoadjuvant chemotherapy [AC-D(H)] protocol of four cycles of doxorubicin plus cyclophosphamide (AC) combination chemotherapies followed by four ...
A new study adds to the evidence that chemotherapy enhances cancer's spread beyond the primary tumor, showing how one chemo drug allows breast cancer cells to squeeze through and attach to blood vessel linings in the lungs.
Carol Kwok, who led the study, said that pre-surgery chemotherapy may bring "new hopes" for breast cancer patients as a higher pathological complete response (PCR) rate was observed in some aggressive tumor types such as the HER2-positive and the triple-negative breast cancers. ...
End points were death for OS and death or any recurrence of breast cancer for DFS. The original trial design had two randomly assigned treatment protocols: a high-dose chemo-therapy arm and a standard chemotherapy arm, as described above. Survival comparisons between groups have been published (...
b, c Expression of ZEB1 in chemoresistant tumors were significantly higher than that in non-resistant tumors. d, e The non-negative percentage analysis for Bcl-xL indicates a positive correlation with ZEB1 expression in primary breast cancer. f, g The non-negative percentage analysis for Cyclin...