Between 2013 and 2015, the use of chemotherapy for early-stage breast cancer in the United States significantly decreased, according to a new survey of women from two Surveillance, Epidemiology, and End Results (SEER) registries. The decline has occurred without a substantial change in practice ...
When clinically indicated, chemo use high for breast cancerCompanyJaapa
Cancer patients know chemotherapy can be a life-saver, but the side effects are notorious. One common complaint is that the treatment leaves them feeling foggy-headed and forgetful, unable to concentrate or focus as well as they used to. It's been nicknamed "chemo brain." Chemotherapydrugs ca...
Metaplastic breast cancer is a highly chemoresistant breast cancer subtype with limited therapeutic options. Here, the authors report that the NOS inhibitor, L-NMMA, sensitises metaplastic breast cancer to a selective PI3K inhibitor, alpelisib, and taxane chemotherapy via repression of c-JUN mediated...
production of certain hormones in the body. The drug is used to treat prostate cancer and breast cancer, diseases that are sensitive to hormones, by suppressing the production of the sex hormones estrogen and testosterone. It is also used by women who undergo procedure...
Although our focus is chemotherapy, it should be noted that breast cancer also frequently develops resistance to hormone therapy and the newer drugs for targeted therapy such as trastuzumab [23, 24], hence this is a common phenomenon with long-term use of practically any choice of drug. A bro...
Combinations of anti-cancer drugs can overcome resistance and provide new treatments1,2. The number of possible drug combinations vastly exceeds what could be tested clinically. Efforts to systematically identify active combinations and the tissues and m
Breast Cancer Chemo Is Often Unnecessary—but Doctors May Not Want You to Know BYElisabeth Rosenthal September 6, 2018 at 9:00 PM GMT+8Doramay Bailey (CQ), 58, is treated for stage four breast cancer at City of Hope in Duarte on August 11, 2010. After having an abnormal mammogram she...
Because depletion of ZEB1 chemosensitizes breast cancer cells in vitro and in vivo, we suggest that ZEB1-targeting agents have the potential to be used as tumor chemosensitizers. Moreover, various ATM inhibitors are being tested in anti-cancer treatment63, which warrant investigation as candidate ...
Carol Kwok, who led the study, said that pre-surgery chemotherapy may bring "new hopes" for breast cancer patients as a higher pathological complete response (PCR) rate was observed in some aggressive tumor types such as the HER2-positive and the triple-negative breast cancers. ...