She maintains an active clinical practice at the University of California San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center, where she is a professor in the Department of Medicine and the director of breast oncology and clinical trials. At UCSF, she leads the Breast Forum, a ...
UCSF Helen Diller Family Comprehensive Cancer Center, 1450 3rd St, San Francisco, CA, 94158, USA Alan Ashworth Contributions G.D.C. and D.N. analysed the data. I.S. generated the data. G.D.C., D.N. and I.S. interpreted the results and contributed to manuscript preparation. H.T.,...
Cancer cell adaptation to stresses such as nutrient deprivation, hypoxia, and chemotherapy can critically contribute to dormancy, metastasis, therapy resistance, and recurrence. Identifying mechanisms that govern cellular adaptation, plasticity, and the emergence of stem-like cancer cells may be key to e...
ARTICLE Received 28 Jan 2014 | Accepted 6 May 2014 | Published 17 Jun 2014 DOI: 10.1038/ncomms5051 OPEN 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy Jingmei Li1,2,*, Linda S. Lindstro¨m3,4,* et al.# Large population...
et al. “UCSF 4Hs version 2 human long oligo array”, Gene Expression, 2003, 397 pages. probes ID: HD200001112, H200005758, HD200007211. Desmedt, C. et al. “Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter...
Large population-based registry studies have shown that breast cancer prognosis is inherited. Here we analyse single-nucleotide polymorphisms (SNPs) of genes implicated in human immunology and inflammation as candidates for prognostic markers of breast c
Open Babel GUI (O’Boyle et al., 2011), UCSF Chimera 1.8.1, PubChem (www.pubchem.com, accessed on 15 November 2021), RCSB PDB (http://www.rscb.org/pdb, accessed on 20 December 2021), AutoDock/vina software (https://vina.scripps.edu, accessed on 1 May 2022) [54], and Discov...
Many thanks to Jason Koutcher, Inna Serganova, and Natalia Kruchevsky at Memorial Sloan Kettering Cancer Center for generously providing and arranging delivery of the 67NR cell line to our lab. Thank you to Amy Frees Martinez for assistance in statistical analysis. Thank you to Roman Camarda ...
2 Department of Biology, Duke University, Durham, NC 27708, USA; jduer@wakehealth.edu 3 Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, CA 94143, USA; joyce.lee3@ucsf.edu (J.V.L.); jeremy.williams@ucsf.edu (J.W.); baris.av...