This chapter explains that hemoglobin is made up of heme, an iron containing porphyrin and globin, a protein. Normally the erythrocyte lives about 120 days. As the life span of erythrocytes is not increased in splenectomized patients, these sites can completely take over the function in the ...
Therefore, neurons may be exposed to hemoglobin and/or its breakdown products, hemin and iron, for long periods of time. In this study, the electrophysiological actions of these agents on synaptic transmission in rat hippocampal CA1 pyramidal neurons were studied using extracellular field- and ...
This study evaluated the damage to the endothelial tight junctions (TJs) in pregnancies complicated by fetal growth restriction (FGR) and investigated whether FGR is related to blood–brain barrier disintegration and, subsequently, to the appearance of proteins indicative of neuronal injury in maternal...