Prognosis and clinical presentation of BRCA2 -associated breast cancer. Eur. J. Cancer 36 :1365-1373.Loman N, Johannsson O, Bendahl P, Dahl N, Einbergi Z, Gerdes A, Borg A, Olsson H. 2000. Prognosis and clinical presentation of BRCA2-associated breast cancer. Eur J Cancer 36:1365-...
Oestrogen receptor status, treatment and breast cancer prognosis in Icelandic BRCA2 mutation Carriers. Br J Cancer. 2016;115(7):776–83. Article PubMed PubMed Central CAS Google Scholar Olafsdottir EJ, Borg A, Jensen MB, Gerdes AM, Johansson ALV, Barkardottir RB, et al. Breast cancer ...
that testing forBRCA1/2PVs in individuals with breast cancer may in some instances have been influenced by the presence of PCa cases in the family. If so, failing to adjust for the PCa events that determined the ascertainment would bias the resulting PCa RRs away from the null. One study ...
Current treatment modalities for incident cases do not differ for age- and stage-matched sporadic breast cancer cases; although clinical trials with PARP inhibitors are currently underway. ▪ The prognosis for BRCA2-associated breast cancers has not been clearly established Read more View chapterExplo...
Define BRCA2. BRCA2 synonyms, BRCA2 pronunciation, BRCA2 translation, English dictionary definition of BRCA2. abbr. flavin adenine dinucleotide n. A fashion that is taken up with great enthusiasm for a brief period of time; a craze. fad′dism n. fad′dis
prognosiswild type allele lossadjuvant treatmentOverexpression of the Aurora A kinase has been shown to have prognostic value in breast cancer. Previously, we showed a significant association betweenAURKAgene amplification andBRCA2mutation in breast cancer. The aim of this study was to assess the ...
Breast cancer patients who carry the Icelandic founder BRCA2 mutation have inferior long-term survival than noncarriers, but the adverse prognosis is restricted to mutation carriers with diploid, slowly proliferating tumours.SpringerBreast Cancer Research & Treatment...
Impact of germline DNA repair gene variants on prognosis and treatment of men with advanced prostate cancer Article Open access 06 November 2023 Germline sequencing in men with metastatic castration-resistant prostate cancer from the BARCODE2 study reveals a wide range of pathogenic variants in DNA...
［摘 要］目的：探讨ＢＲＣＡ２蛋白表达与乳腺癌临床病理特征的关系。方法：选取９７例乳腺浸润性导管癌患者蜡块组织和３０例癌旁正常乳腺组织（对照），用免疫组化技术检测２种组织中ＢＲＣＡ２蛋白表达，同时比较ＢＲＣＡ２蛋白表达与患者临床病理特征（年龄、肿瘤大小、分子分型、月经情况、病理分级、淋巴结...
The discovery of the first gene associated with hereditary breast cancer, BRCA1, was anticipated to greatly increase our understanding of both hereditary and sporadic forms of breast cancer, and to lead to therapeutic and preventive breakthroughs. Much has been learned during the past decade about ...