参考文献 Nen NR, Reisel D, Leimbach A, et al. Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study[J]. Lancet Oncol, 2019. 责任编辑:Linda
ovarian cancerBRCA1BRCA2associationSNPGermline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian cancer. A genome-wide association study (GWAS) identified six alleles associated with risk of ovarian cancer for women in the general population. We evaluated four ...
[2]Kuchenbaecker KB, Hopper JL, Barnes DR, et al. Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers. JAMA. 2017;317(23):2402-2416. doi:10.1001/jama.2017.7112 [3]Oh M, Alkhushaym N, Fallatah S, et al. The association of BRCA1 and BRCA...
[2]Kuchenbaecker KB, Hopper JL, Barnes DR, et al. Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers. JAMA. 2017;317(23):2402-2416. doi:10.1001/jama.2017.7112 [3]Oh M, Alkhushaym N, Fallatah S, et al. The association of BRCA1 and BRCA...
cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer but, unlike BRCA1, does not confer a substantially elevated risk of ovarian cancer. The BRCA1 gene is expressed in numerous tissues, ...
[2]Kuchenbaecker KB, Hopper JL, Barnes DR, et al. Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers. JAMA. 2017;317(23):2402-2416. doi:10.1001/jama.2017.7112 [3]Oh M, Alkhushaym N, Fallatah S, et al. The association of BRCA1 and BRCA...
[6]. Lønning PE, Nikolaienko O, Pan K, et al. Constitutional BRCA1 Methylation and Risk of Incident Triple-Negative Breast Cancer and High-grade Serous Ovarian Cancer [published online ahead of print, 2022 Sep 8]. JAMA Oncol. 2022;e223846. doi:10.1001/jamaoncol.2022.3846 ...
[6]. Lønning PE, Nikolaienko O, Pan K, et al. Constitutional BRCA1 Methylation and Risk of Incident Triple-Negative Breast Cancer and High-grade Serous Ovarian Cancer [published online ahead of print, 2022 Sep 8]. JAMA Oncol. 2022;e223846. doi:10.1001/jamaoncol.2022.3846...
[1[Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer.[J]. New England Journal of Medicine, 2018. [2]2020 ESMO Abs 811MO [3]2020《NCCN Clinical Practice Guidelines in Oncology: Genetic/Familial High-Risk Assessment: Breast and Ovarian》...
miki y, swensen j, shattuck-eidens d, et al. a strong candidate for the breast and ovarian cancer susceptibility gene brca1[j]. science, 1994, 266(5182): 66-71. doi:10.1126/science.7545954 [2] wooster r, big...