The nation's biggest medical lab testing firm, Quest Diagnostics, plans to offer a test for BRCA gene mutations, which are linked to increase risk for breast and ovarian cancers. The test will be made available at the company's 2,100 testing centers throughout the country, which serve about...
Quest Diagnostics Healthcare professionals Clinical Education Center FAQ BRCA Panel Plus Test code(s) 92587 Reference National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®). Genetic/familial high-risk assessment: breast, ovarian, and pancreatic. Version 1....
We developed an assay using random shearing of genomic DNA followed by RNA bait tile hybridization and NGS sequencing on both the Illumina MiSeq and Ion Personal Gene Machine (PGM). We determined that the MiSeq Reporter software supplied with the instrument could not detect deletions greater than...
BRCA1/2genetic testing, which has been in use for nearly two decades, still produces VUS results regularly [2]. Multi-gene panels and WGS/WES will inevitably increase the number of VUS found because more genes are included in the analyses [3],[4]. In comparison withBRCA1/2, there wil...