BRCA1 and BRCA2 mutations are associated with a higher risk of breast and ovarian tumors. This study evaluated the emotional states of women 1 month after having received the results of the genetic test and assessed eventual associations with the type of outcome, personal/familiar disease history...
When parents disclose BRCA1/2 test results: their communication and perceptions of offspring response. Cancer 2012;118(13):3417-25.A. R. Bradbury, L. Patrick-Miller, B. L. Egleston et al., "When parents disclose BRCA1/2 test results: their communication and perceptions of offspring ...
In the ten years since the discovery of BRCA1 and BRCA2, genetic testing for breast and ovarian cancer susceptibility has become integrated into the practice of clinical oncology. Attempts to identify a third breast cancer susceptibility locus (BRCA3) have so far been unsuccessful. This is probab...
To our knowledge, ours is the first examination of willingness to test and actual testing behaviour among women at high risk of breast cancer, involving perceived risk, family risk, and numeracy, both subjective and objective. To accomplish this, we recruited women with a family history of breas...
Presymptomatic testing for BRCA1 and BRCA2:how distressing are the pre-test weeks?L N Lodder, P G Frets, R W Trijsburg, E J Meijers-Heijboer, J G M Klijn,H J Duivenvoorden, A Tibben, A Wagner, C A van der Meer, P Devilee, C J Cornelisse,M F Niermeijer, and other members...
Who (and what) to test forBRCAmutation The value of gBRCA1/2m testing for cancer risk reduction in breast and ovarian cancer is well-established.17,18,19To date, researchers from the Breast Cancer Information Core (https://research.nhgri.nih.gov/bic/) have collated more than 1800 mutations...
This cohort study estimates age-specific risks of breast, ovarian, and contralateral breast cancer among carriers of BRCA1 and BRCA2 mutations and
pg 2 P4 Test Announcement Tests now available in the clinical laboratory Full Article... pg 4 P5 Journal Watch Summaries of recent topical publications in the medical literature Full Article... pgs 5 Era of new diagnostic approaches: BRCA1 and BRCA2 genes Author: Anna Shurshalina, MD, PhD....
Journal of Genetic Counseling (2018) 27:1459–1472 https://doi.org/10.1007/s10897-018-0261-5 ORIGINAL RESEARCH Patients' Views of Treatment-Focused Genetic Testing (TFGT): Some Lessons for the Mainstreaming of BRCA1 and BRCA2 Testing Sarah Wright1 & Mary Porteous2 & Diane Stirling2 & ...
When applied to mutations in BRCA1 and BRCA2 genes,which can predict a high risk for breast and ovarian cancer, the SNP test only had a positive predictive value of 4.2%, according to the studypublished Mondayin the journal BMJ Open Access. ...