Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetesIncreased levels of branched-chain amino acids (BCAAs) are associated with type 2 diabetes pathogenesis. However, most metabolomic studies are limited to...
Branched-Chain Amino MetabolismThe branched-chain amino acids (BCAAs) leucine, isoleucine, and valine are known to enhance protein synthesis and improve energy homeostasis. While BCAAs cannot be synthesized endogenously, they are subjected to transamination by the branched-chain aminotransferases (BCATs...
et al. Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness. Metabolism 62, 961–969 (2013). CAS PubMed PubMed Central Google Scholar Huang, Y., Zhou, M., Sun, H. & Wang, Y. Branched-chain amino acid metabolism in heart disease: an epiphenomenon or...
disorder of branched chain aminoacid metabolism分享到: 支链氨基酸代谢病分类: 遗传学 | 查看相关文献(pubmed) | 免费全文文献 详细解释: 由于线粒体支链α-酮酸脱氢酶缺乏引起的疾病。以下为句子列表:分享到: 赞助商链接 你知道它的英文吗? ·正优生学 你知道中文意思吗? 热门分类 ·常用8000词汇 ...
Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D). Several studies showed elevated plasma BCAA levels in humans with insulin resista
Nature Metabolism1,532–545 (2019)Cite this article 14kAccesses 220Citations 536Altmetric Metrics Abstract Elevated branched-chain amino acids (BCAAs) are associated with obesity and insulin resistance. How long-term dietary BCAAs impact late-life health and lifespan is unknown. Here, we show tha...
(2004). Regulation of branched-chain amino acid metabolism and pharmacological effects of branched-chain amino acids. Hepatol. Res. 30S, 3-8.SHIMOMURA, Y.; MURAKAMI, T.; NAGASAKI, M.; HONDA, T.; GOTO, H.; KOTAKE, K.;KUROKAWA, T.; NONAMI, T. Regulation of branched-chain amino acid...
Sweatt AJ, Garcia-Espinosa MA, Wallin R & Hutson SM 2004a Branched-chain amino acids and neurotransmitter metabolism: expression of cytosolic branched-chain aminotransferase (BCATc) in the cerebellum and hippo- campus. Journal of Comparative Neurology 477 360-370. (doi:10.1002/cne.20200)...
Branched-chain Amino Acid Metabolism Is Impaired in Mice and Humans with Alzheimer's Disease (OR27-04-19) 来自 ResearchGate 喜欢 0 阅读量: 40 作者:MAB Siddik,MZ Moghaddam,V Hegde,A Shin 摘要: Objectives: Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that is the ...
Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D). Several studies showed elevated plasma BCAA levels in humans with insulin resista