There was a drawback, however, with the shear wave scans only detecting tumour tissue with a 77% specificity – better than the 63% for 2D ultrasound, but not on par with the 100% success rate of the surgeons. This means that the new approach risks yielding false positives but, as the...
25 In another prospective randomized study, patients with two to four brain metastases were randomized to initial brain tumour management with WBRT alone or WBRT plus Gamma Knife radiosurgery. The study was stopped at an interim evaluation at 60% accrual, since the rate of local failure at 1 ...
Functional neuronavigation indicating the tumour margins and the motor and sensory evoked fields was possible in all patients. Conclusion: The SEP phase reversal of N20-P20 is a simple and reliable technique, but the success rate is much lower in large central and postcentral tumours. With the ...
hampering the life quality of patients. Brain-targeted drug delivery is challenging, with a low success rate this far. Therefore, the application of targeting ligands in drug vehicles, such as lipid-based and polymeric nanoparticles, holds the promise to overcome the blood-brain barrier ...
Detecting a brain tumour at the earliest possible stage enables faster treatment and safer surgery, which are essential to improve the patient’s chance of a good clinical outcome. But brain tumour diagnosis is a difficult task, as common symptoms such as headaches or memory change are not speci...
Brain metastasis leads to poor outcomes and CNS injury, significantly reducing quality of life and survival rates. Advances in understanding the tumor immune microenvironment have revealed the promise of immunotherapies, which, alongside surgery, chemoth
Brain tumor diagnosis mostly relies on magnetic resonance imaging or positron emission tomography [43]. The current point of care therapy for primary brain tumors includes surgery, followed by radio-chemotherapy that only improves the average patient’s survival by 5 years [44]. Unlike other cancers...
Steeg, P. S. The blood-tumour barrier in cancer biology and therapy.Nat. Rev. Clin. Oncol.18, 696–714 (2021). ArticlePubMedGoogle Scholar , 50–58 (2018). ArticleCASPubMedGoogle Scholar 40, 169–177 (2017). PubMed CentralGoogle Scholar ...
necessitate tailored treatment strategies based on the specific characteristics of each tumor. Treatment modalities may involve a combination of surgery, radiation therapy, and chemotherapy, with the goal of managing and mitigating the tumor’s impact on neurological function [3]. The sample image of ...
Sex differences in human health and disease can range from undetectable to profound. Differences in brain tumor rates and outcome are evident in males and