Data suggest that when activated by glioma cells, microglia have reduced phagocytic potential compared to microglia in homeostasis [141,142,143]. These findings provide early proof that microglia are reprogrammed in the tumor microenvironment. However, even under normal conditions, microglia in different...
To explore the influence of age on steady-state inflammation and senescence, we analyzed the expression of 800 genes using the NanoString nCounter mouse neuroinflammatory codeset and a custom senescence and aging codeset in the hippocampus, subventricular zone enriched-striatum, and cerebellum of 6-mo...
Prevalence estimates population‐level cancer burdens at a specified time. This study estimates the prevalence of malignant and non‐malignant BTs in comparison to other cancers. Methods Incidence data were obtained from the Central Brain Tumor Registry of the United States (2000–2019, varying), a...
The exclusion criteria included age < 65 years, CDR = 0, having difficulty performing basic activities of daily living, under treatment for cancer in the prior 3 years, brain CT showed an organic brain lesion such as hematoma, brain tumor, acute stroke, or post-infarction encephalo...
Parkinson’s disease (PD) is the second most common NDD after AD, with a prevalence of approximately 2 per 1000 individuals worldwide [80,81]. PD is characterized by the loss of dopamine in the substantia nigra and the dysregulation of fine motor control localized in the basal ganglia, whic...
On what date did you have your brain injury? At what age? January 4, 1995 I was 24. How did your brain injury occur? Nasty car accident When did you (or someone) first realize you had a problem? Immediately. I was unconscious and paralyzed. ...
The prevalence of dementia increases exponentially with age. The global prevalence of dementia is about 0.7–1.8% in population aged 60–64 years, while in people aged over 90 years the figure is between 28.7% and 63.9% [1]. Alzheimer’s disease (AD) is the most common type of ...
3. Duffner PK, Horowitz ME, Krischer JP, et al: Postoperative chemotherapy and delayed radiation in children less than three years of age with malignant brain tumors. N Engl J Med 328:1725-1731, 1993. Articles in this issue Prevalence of Substance Abuse Disorders in Cancer Patients ...
In particular, the combination of brain morphology and behavioral testing of cohorts is a challenge for the future. Moreover, they may help to explain sex differences in the prevalence and progression for a number of disorders, diseases, and disabilities....
et al. Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys. JAMA 291, 2581–2590 (2004). Article PubMed Google Scholar Tsang, A. et al. Common chronic pain conditions in developed and developing countries: gender...