But how neuroanatomy impacts performance is largely an open question. To learn more, scientists are developing a new tool—computational models of the brain—to simulate how the structure of the brain may impactbrain activityand, ultimately, human behavior. The research focuses on interconnectivity wi...
including alcohol consumption, diet, physical activity, sleep, smoking, sedentary behavior and social connection, that contribute to depression, and examine the underlying neurobiological
Data from more than 1300 participants demonstrate that the LODESTARS has a two-factor (reward, threat) structure and excellent psychometric properties, including high test–retest reliability and measurement invariance across gender40. The LODESTARS yields two scores for each participant: a social rew...
Moreover, many other investigations also revealed that microgravity strongly affected the structure and physiology of brain[7-10]. Considering the irreplaceable role of brain in human activities, it is of great importance to further explore the impacts of microgravity and underlying mechanism on brain...
As the input current level increases, the output firing rate increases linearly (blue) or nonlinearly (purple), depending on the resistance behavior Full size image The computational power of the brain stems from the large number of these synaptic connections. The estimated number of neurons in ...
75. Disruption of synchronized activity at several scales may explain the paradoxical observation that psychedelics produce an increase in metabolic activity19,20, a decrease in the power of local fluctuations22,76and a loss of the brain’s segregated network structure23,56. This desynchronization of...
"When we launched this project in the 1970s, the field knew more about how to assess behavior than it knew about how to assess brain structure," Craig Ramey said. "Because of advances in neuroimaging technology and through strong interdisciplinary collaborations, we were able to measure structur...
Endoplasmic reticulum stress and disrupted neurogenesis in the brain are associated with cognitive impairment and depressive-like behavior after spinal cord injury 2016, Journal of Neurotrauma Persistent changes in neuronal structure and synaptic plasticity caused by proton irradiation 2015, Brain Structure an...
Clinically significant impairment or distress was defined as having at least one positive response to the following two questions in the YFAS questionnaire: “My behavior with respect to food and eating causes significant distress” and “I experience significant problems in my ability to function ...
behavior and memory dysfunction. However, it is unclear whether upregulation of VGF affects brain function. In the present study, we generated mice that overexpress VGF and investigated several behavioral phenotypes and the brain structure. These adult VGF-overexpressing mice showed (a) hyperactivity,...