Childhood brain tumors are the leading cause of cancer-related morbidity and mortality in the pediatric years and differ from primary central nervous system tumors occurring in adults. Management strategies must take into account not only the tumor type, but the age of the patient and the likelihoo...
G. HaferkampSpringer Berlin HeidelbergHaferkamp G (1986) Chemotherapy of malignant brain stem tumours in adults — new substances, prospect. In: Samii M (ed) Surgery in and around the brain stem and the third ventricle. Springer, Berlin Heidelberg New York, pp 582–587....
One form of astrocytoma is called glioblastoma multiforme (GBM). This tumor type can start in several types of cells, including your astrocytes and oligodendrocytes. These tend to grow very fast and spread to other tissues. They're most common in people 50-70 years old, especially men and pe...
Table 5.CEREBRAL BLOOD FLOW AND METABOLIC RATE IN HUMANS WITH VARIOUS DISORDERS AFFECTING MENTAL STATE ConditionMental stateCerebral blood flow (ml/100g/min)Cerebral O2consumption (ml/100g/min) NormalAlert543.3 Increased intracranial pressure (brain tumor)Coma34*2.5* ...
The most common types of primary brain tumors in children are medulloblastoma, grade I or II astrocytoma, (or glioma) ependymoma, and brain stem glioma. Symptoms of Brain tumor: Symptoms of brain tumors depend on the location and size of the tumor. Some tumors cause direct damage by invading...
Alberto Costa, in Cellular, Molecular, Physiological, and Behavioral Aspects of Traumatic Brain Injury, 2022 Mini-dictionary of terms ● Acquired brain injury: it is a brain injury occurred after birth, with different etiology (anoxia, bleeding, infection, hypoxia, ischemia, and tumor) ● ...
It also follows the need to target a specific target or group of targets present in cells, which can also be used as cell-specific targeting [94]. MDVs were initially developed to treat certain types of tumors, which harbor cancer stem cells in their core and produce extensive layers of ...
Glioblastoma (GBM), a WHO grade IV glioma, is the most common malignant brain tumor in adults and portends an extremely poor prognosis despite aggressive therapy with maximal surgical resection, radiotherapy, and chemotherapy. GBM is most common in older adults, with highest rates seen in ...
Additionally, brain cancer stem cells (BCSC), the subclass of self-renewing, tumorigenic cancer cells, can also contribute to this immunomodulatory response (e.g., secretion of periostin for increased recruitment of tumor-supportive microglia and macrophages) [61], [62], [63], [64]. BCSCs ar...
CURE’s brain cancer page features the latest cancer news and updates on brain cancer Through articles, videos, podcasts, and more, CURE brings readers the insights of experts, cancer survivors, patients, and advocates to ensure everyone is up to date in brain cancer....