(BBB) disruption is associated withcerebral ischemiaand leads to vasogenic edema, a primary cause of stroke-associated mortality. To date, only a single drug has received US Food and Drug Administration (FDA) approval for acuteischemic stroketreatment,recombinant tissue plasminogen activator(rt-PA)....
Sleep Disorders And Neuroscience Of Sleep Spinal Cord Injuries Stem Cells And Regenerative Neuroscience Stroke And Ischemic Brain Injury Substance Use And Addiction Suicidality And Suicide Prevention Synaptic Transmission And Plasticity Traumatic Brain Injury (TBI) Wearable Technology In Neurology443308187501...
infections, tumors, toxins,arteriovenous malformations, trauma, and use of opioids.Brain deathcan occur when the blood, oxygen supply, or both to the brain have stopped. These conditions include cardiac arrest,myocardial infarction, stroke,blood clots, severehead injuries, encephalitis, and brain ...
BBB disruption is commonly presumed reversible after harmful insults are removed; however, re-establishment of the BBB integrity after stroke is incomplete [289], and could influence rehabilitation, increase the risk of repeated stroke, and further develop to vascular dementia. Therefore there is an ...
Neuro-oncology is defined the study of brain and spinal cord neoplasms, many of which are (at least eventually) very dangerous and life-threatening (astrocytoma, glioma, glioblastoma multiforme, ependymoma, pontine glioma, and brain stem tumors are among the many examples of these). Among the ma...
Heterogeneity and transcriptome changes of human CD8+ T cells across nine decades of life. Nat. Commun. 13, 5128 (2022). Article CAS Google Scholar Faiz, M. et al. Adult neural stem cells from the subventricular zone give rise to reactive astrocytes in the cortex after stroke. Cell Stem...
The increase in life expectancy is one of the highest accomplishments of humankind. Yet, this situation is also one of the most challenging public health issues. Despite the inevitable advancement of biological age, the deterioration of physiological hom
In normal or disease conditions, neurogenesis involves four general cellular events: i) proliferation of stem/progenitor cells; ii) migration of stem/progenitor cells into different areas of the central nervous system; iii) differentiation into specific neuronal cell types; iv) integration in the esta...
Keywords: biomaterials; hydrogels; stem cells; stroke; brain repair 1. Introduction In recent decades, considerable progress has been made in the development of experimental therapies to treat different brain disorders. Among the different approaches examined, cell therapy has been configured as a ...
blood-brain barrier; ischemic stroke; nanoparticles; neuroprotection; stroke prevention1. Introduction Nowadays, neurological diseases are considered the leading cause of decrease in life expectancy due to disability and the second cause of death worldwide [1,2,3]. These processes are growing at a ...