Electrodes are labeled with both a letter (for example F for frontal, C for central, P for parietal, T for temporal, et cetera) and a number (even for right and vice versa) according to the site at which they record the brain activity. Although EEG signals have poor spatial resolution ...
If peripheral inflammation is sensed and transmitted by the vagus nerve to the cNST, then blocking the transfer of vagal signals should abolish LPS-evoked neural activity in the cNST. Indeed, bilateral subdiaphragmatic transection of the vagus nerve5,34eliminated cNST responses to LPS (Fig.1c). ...
If no single label is predicted by more than half the methods, the cell is labeled as ‘unannotated’. Differential expression analysis was conducted on the ‘cell_type’ parameter using the FindMarker function from Seurat (v4.1.1)61 using the Wilcoxon test. Hierarchical cell type annotation ...
Primates exhibit complex brain structures that augment cognitive function. The neocortex fulfills high-cognitive functions through billions of connected ne
Bottom: percent labeled glucosamine in glycogen isolated from astrocytes cultured in 2 mM 13C-glucosamine for up to 8 h. Data shown are representative of three experiments. (E) Top: schematic of in vitro tracing of glucosamine (GlcN) incorporation into glycogen using 13C6-glucose. G-13C-Gl...
To further characterize the developing midbrain neuroepithelia, we labeled proliferating progenitor cells with EdU and stained for OTX2, a transcription factor that separates the midbrain from the hindbrain. OTX2 expression was observed in cells within the apical surface and extended to the ...
Human cerebral organoids undergo vascularization and maturation in the mouse brain. Differentiation of human pluripotent stem cells to small brain-like structures known as brain organoids offers an unprecedented opportunity to model human brain developme
Further, autoradiographic paradigms were used to measure the accumulation of 14C-labeled 5-HT analogue α-methylserotonin and quantify changes in the rate of 5-HT synthesis. Three days post-injury (DPI) corresponded to both the period of lowest glucose utilization and the period of greatest 5-...
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Functional connectivity was cal- culated as the Pearson's correlation between the averaged signal in the labeled brain areas that include 246 regions with 74, 34 and 15 areas in each hemisphere of the cortex, basal ganglia and hippocampus, respectively. The con- nectivity matrix was calculated ...