The article discusses the use of deep-brain stimulation (DBS) to cure depression. DBS involves drilling a hole in the skull and inserting an electrode into a patient's brain tissue. This treatment was consi...
This is known as treatment-resistant depression, and brain stimulation therapies can be life-changing for people who experience it. “Brain stimulation therapies involve the application of [electric] energy over specific brain regions to modulate the function of neural circuits,” Joshua Berman, M.D...
Despite this stigma, ECT is ahighly effective treatment for depression—up to 80% of patients experience at least a 50% reduction in symptom severity. For one of themost disabling illnessesaround the world, I think it's surprising that ECT israrely usedto treat depression. Contributing to the...
One of the most disappointing failures of a putative treatment for depression was the NK-1 antagonist, which was extensively studied preclinically and in exploratory and confirmatory clinical trials, with the most comprehensive program involving the Merck drug candidate MK-0869. This program included ...
From shock treatment to deep brain stimulation(刺激), there is a long history of applying electrical currents to the brain to treat mental health issues. Now two studies suggest the benefits of this type of treatment might be more widespread. In one experiment, researchers used electrodes(电极)...
It further evaluates relevant methodological aspects of today's research in DBS for TRD. On the scientific side, the reward system has an important yet clearly under-recognized role in both neurobiology and treatment of depression. On the methodological side of DBS research in TRD, better animal ...
stimulationwithelectroconvulsive therapy, a procedure used for patients with severe depression or catatonia. With electroshock therapy, the anesthetized patient receives a directelectrical current, which causes a seizure. Typically, people who undergo this procedure experiencesome memory loss after treatment....
GABA (Gamma-Aminobutyric Acid) is the brain’s primary inhibitory neurotransmitter responsible for calming the nervous system. Low levels of GABA have been linked to many conditions, including anxiety, depression, seizures, and movement disorders. ...
METHOD FOR THE TREATMENT OF GOUT OR PSEUDOGOUT The present invention relates to a new method, and the process to manufacture a medicament, for treating gout or pseudogout, comprising administering an effective amount of inhibitors blocking IL-1 or its maturation by the NALP3 inflamma... V Pet...
Deep brain stimulation (DBS) as a putative approach for treatment-resistant depression (TRD) has now been researched for about a decade. Several uncontrolled studies—all in relatively small patient populations and different target regions—have shown clinically relevant antidepressant effects in about ha...