To investigate the effect of lentivirus transduction on cellular physiology, we analyzed 195 genes expressed during virus infection (KEGG pathway: mmu05170). We downsampled the dataset such that each cell type per condition contained an equal number of cells. We plotted expression values of non-zer...
Summary This final short chapter makes an introductory discussion of some physical aspects of brain physiology. Following on from the consideration of spikes and the senses the neural encoding inverse problem is first approached, i.e. how to reconstruct the sensory information transmitted by a series...
The content spans a broad range of research fields, from neuroscience to immunology, from physiology to behavioural sciences, from psychiatry and psychology to clinical medicine, from molecular and cellular models to social and epidemiological observations. Publications include research articles, reviews, ...
brain physiology and inter-individual differences, notably those including the interaction with a human-specific virus as HIV-1. Therefore, developing an appropriate experimental model with relevant human neuronal cell lineages remains a high priority, since no therapeutic treatments are available to ameli...
1). The physiology and impact of the BBB in CNS pharmacology has been reviewed in depth elsewhere [7–12]. The BBB controls the flow of molecules between blood and brain extracellular fluid, and part of its function is to protect the brain from toxins, including xenobiotics. The barrier's...
physiologyBetween childhood brain’swiring diagram becomes richer more complexand more efficient especially brain’sfrontallobe frontouter mantle which seatofsuch higher order functions socialization importantpart ofthe frontal lobes isthe prefrontal cortex PFC which oftenreferredto executiveofthe brain ...
of neurology, but to know them thoroughly".This objective was achieved admirably, with a clarity of style characteristic of the author, an ability to summarise a complicated situation in a few well-chosen paragraphs (e.g. the anatomy and physiology of the extrapyramidal system in two pages!)...
(a) Diagram of the decoding pipeline. First, neural activity (multiunit threshold crossings) was binned on each electrode (20-ms bins). Then, a trainable day-specific linear input layer transformed the binned activity from a specific day into a common space to account for day-to-day ...
The neuropeptide corticotropin releasing factor/hormone (CRF/CRH), first discovered in the early 1980s [10], is an important modulator of stress-associated physiology and behavior [11,12,13,14,15]. Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis is observed in mood disorders such...
Morphology and physiology of the cerebellar vestibulolateral lobe pathways linked to oculomotor function in the goldfish J. Neurophysiol., 96 (2006), pp. 1963-1980 CrossrefView in ScopusGoogle Scholar Walls, 1962 G. Walls The evolutionary history of eye movements Vision Res., 2 (1962), pp. ...