Brain Delivery of Drug and MRI Contrast Agent: Detection and Quantitative Determination of Brain Deposition of CPT-Glu Using LC-MS/MS and Gd-DTPA Using Magnetic Resonance Imaging. Molecular pharmaceutics. 2016 Feb 01;13(2):379-90. doi: 10.1021/acs.molpharmaceut.5b00607. PubMed PMID: ...
Moreover, a recent MRI-based study of astronaut brains found that spaceflight induced ventricular expansion in the brain91. Finally, increased hippocampal apoptosis and aquaporin-4 expression have been observed in other studies75, along with significant increase in the expression of PECAM-1 and ...
No effects on CN, or TBV. No interactions between ADHD status and genotype. Durston et al. (2005) 3’UTR and intron 8 VNTR haplotype, exon 3 VNTR sMRI Striatum, frontal cortex, and hippocampus volumes 10-6 haplotype carriers vs. non-10-6 haplotype carriers, 7R-carriers vs. non–7R-...
However, this kind of gap-dependent permeability merely exists in WHO-defined grade II astrocytomas and oligodendrogliomas vessels [19], which leads to low permeability of contrast agents for CT and MRI and following faint contrast signals in the tumor. Similar to most peripheral tumors, ...
MRI data pre-processing and harmonisation MRI data was pre-processed with Freesurfer 6.0.059,60 to estimate cortical thickness, surface area and subcortical volumes. Data was processed on King’s College London HPC infrastructure Rosalind (https://rosalind.kcl.ac.uk), with the standard recon-all...
Influenza-associated encephalopathy (IAE) is extremely acute in onset, with high lethality and morbidity within a few days, while the direct pathogenesis b
we expected to observe near-transfer effects on visual–spatial working-memory in the whole sample. In contrast, we had no clear expectations of training effects on the other task-related cognitive abilities (executive functioning and mathematical abilities) and on quality of life and psychological ...
(group × time interaction, P = .47) with the posttreatment contrast between CBTH and TPU decreasing −0.5 units (95% CI, −2.9 to 1.9) at 3 months and −1.7 units (95% CI, −4.1 to 0.7) at 6 months whereas the posttreatment contrast between CPT and TPU increased 1.2 ...
WISC and CPT scores are expressed relative to a normative population. #: number of parameters below the norm. Values in red are out of the normal range. 3.2. MRI results High quality 3D T1-weighted MP2RAGE images were obtained for all patients (n = 5 for CLD) and 18 controls (n = ...
15,16 Consequently, all patients with a CPT should undergo magnetic resonance imaging (MRI) with gadolinium contrast of their entire craniospinal axis as part of the initial staging workup. In addition, a diagnostic lumbar puncture for CSF cytology is recommended. Radiologic Appearance CPP and C...