感觉和运动神经都与脊髓中的同类纤维相连,这些纤维又与皮层相连,因此使身体的每一部分都直接与皮层连接。 Fig.12.—Schematic diagram showing association fibers connecting cortical centers with each other.—AfterJamesandStarr. 图12.——示意图,展示了连接皮层中心彼此之间的联合纤维。——根据James和Starr的资料。
Second, structure-function divergence confers considerable flexibility to structural connectome organization: any wiring diagram that guarantees the connection profile of unimodal cortex would be as good as any other in maintaining normal brain function. However, abundant empirical evidence indicates that ...
A diagramatic mid-sagittal view of the atlas showing the ac-pc alignment and RAS coordinate system mapping with XYZ. Full size image Figure 4: A 3D view depicting the RAS coordinate system and the orientation of the brain within it. The letters denote the orientation as follows: (A)nterior...
L, lateral; D, dorsal; V, ventral; ICe, external cortex of the inferior colliculus. PAG and ICe was shaped by dashed lines. b A schematic diagram for Tcf7l2 KO in PAG by AAV-Syn-mCherry-Cre injection. The AAV viral particles were injected into PAG of Tcf7l2 exon11 fl/fl mouse ...
Figure 8. Anatomical and network simulation diagram (A) The connection of a single PFC column. (B) The distribution proportion of different types of neurons in each column layer. (C) Network persistent activity performance. Multi-scale brain structure simulation BrainCog simulates the biological br...
A simplified top view diagram of the LSFM showing its main components and relative optical setup. The close up highlights the approximate rectangular profile of a Gaussian sheet intersection with the specimen. Full size image A physically-plausible simulation of the LSFM requires accurate modelling of...
We then examined the therapeutic value of Il-1β blockage in the humanized mouse model of anti-NMDAR encephalitis. Anakinra, an Il-1 receptor antagonist protein approved for the treatment of rheumatoid arthritis, was used to block Il-1β signaling. The schematic diagram of the experimental design...
The model assuming m110 as a mediator showed significant mediation (upper diagram, red box), whereas an alternative model did not (lower diagram). (B) Bidirectional mediation models testing the relationship of m110 and Aβ burden with APOEε4. The model having Aβ as a mediator showed ...
Strategies and materials for BBB regulation and brain-targeted drug delivery.aSchematic diagram of different mechanisms for BBB crossing.bSchematic diagram of BBB structure.cEngineered materials for brain-targeted drug delivery.dVarious non-invasive strategies for BBB crossing ...
Methods A systematic analysis of the international literature was performed in accordance with PRISMA [18] guidelines (See Supplementary Fig.1for PRISMA flow diagram). The PubMed MEDLINE (National Library of Medicine) database was used to search articles published between January 2000 and December 20...