(b) Between sample variation within a brain region and sample type, as a function of methylation level. (c) Proportion of CpGs with an estimated absolute methylation difference greater than 10% (chosen because CG-DMRs all have an absolute methylation difference > 10%) between the indicated...
As a measure of structure–function coupling of a specific region, we introduce the structural-decoupling index, i.e. the ratio between the norms of \({{\bf{s}}}^{{\rm{D}}}\) and \({{\bf{s}}}^{{\rm{C}}}\) across time. For every individual, the maximal excursion under the...
Includes innovative, clinically-relevant research using neuroimaging approaches to enhance knowledge regarding mechanisms, diagnosis, treatment, and prevention of disorders of higher brain function Provides a platform for discussions on discoveries, advances, and controversies in functional brain imaging and hum...
Results revealed that cerebral cortex was the exclusive region where obvious neuron morphologic changes were induced only by long-term SM. A consistent pattern was also suggested in Bi's study: the ultrastructure of rat cerebral cortex was normal after 7-day SM, but showed significant changes ...
Also, "we were able to identify lowly expressed genes that are critical to cell function," added Zhuang. BUILDING LINKS Now, the team tried to link specific cells with specific behaviors, and they focused on a gene called c-Fos, known as an "immediate early" gene, whose transcription is ...
you might manually have to tell BrainSurfer touse default colors attached to an atlasif the atlas colors from the original visualization do not match the loaded save state. Note, atlases that are loaded as part of the load GUI save state function are “turned off” by default (i.e., hav...
[1]#get the slide that has the desired brain region and coordinates of the center of the regionimageID=structureToImage(datasetID=datasetID,regionIDs=granuleID)#get the closest atlas image.atlasID=imageToAtlas(imageID$section.image.id,imageID$x,imageID$y,planeOfSection='sagittal')#decide ...
links each voxel to its specific brain region. Using this mapping, thehExtractBrainSignalfunction extracts the time series for each brain region by detrending and normalizing the time series data from the voxels that form that particular region. This figure shows an example of a brain signal ...
Due to computational constraints imposed by the large number of genes, we used a Random Forest approach in lieu of Gene Oracle phase 2 for the hypothalamus and cerebellum sets. We used feature_importances_() built in function to output the most important features (i.e. genes), which were ...
a, For the wave model, the activity\(\varphi ({\bf{r}},t)\)at locationrand timetis governed by a wave equation with damping rateγs, spatial length scalersand inputQ. For the neural mass model the activity\({S}_{i}\left(t\right)\)of regioniis described by the functionf, which...