Congresses, Prions, Prion diseases in animals, Prion diseasesCollins, Frank Bastian, Lev G. Goldfarb, and D. Carleton Gajdusek Human Prion Protein GeneMutation at Codon 183 Associated with an Atypical Form of Prion Disease 25 Ricardo Nitrini,Sergio Rosemberg, Maria Rita Passos-Bueno, Luis S. ...
The finding suggests that the number of animals or people that are "silent carriers" of prion diseases may be higher than previously thought. Unlike diseases caused by viruses or bacteria, prion diseases are caused by infectious protein molecules that pass from animals to humans. Although difference...
Human immunodeficiency virus (HIV)-associated dementia (HIVD) has been reported in up to 15% of HIV-infected adult patients. Although the pathogenesis of H... DM Simpson - 《Clinical Infectious Diseases》 被引量: 67发表: 1999年 Spectrum of Opportunistic Infections and Malignancies in Patients ...
Astrocytes are active dynamic signalling players of the brain.Dysfunctions of astrocytes can contribute to the pathogenesis of brain disorders.A common pathological hallmark of several CNS diseases is reactive astrogliosis.Targeting astrocytes represent an alternative approach to develop new therapies. Astrocyt...
Compelling evidence thus shows that dysregulations of astrocyte functions and interplay with neurons contribute to the development and progression of various neurological diseases. Targeting astrocytes is thus a promising alternative approach that could contribute to the development of novel and effective ...
Image analysis Magnetic resonance images were transferred to an independent Windows NT workstation and analyzed using the software packages Analyze (Mayo Foundation, Rochester, Minn) and SPM99 (Cognitive Neuroscience Group, National Hospital for Nervous Diseases, London, England). The intracranial and to...
Certain diseasesaffect only specific cells within the brain. For example, the symptoms ofmultiple sclerosis Bleedinganeurysm Pituitary adenomasare common benign tumors that grow in the sella turcica, where the pituitary gland Both lesions and tumors in the brain represent abnormal areas, but they are...
SHANGHAI, March 12 (Xinhua) -- A group of Chinese brain scientists got inspired by space exploration and designed a real-time analysis system for whole-brain imaging of zebrafish, a model animal used in biomedical research to mimic biological processes or diseases found in humans. ...
Large-scale brain network interactions have been described between trans- and cis-gender binary identities. However, a temporal perspective of the brain's spontaneous fluctuations is missing. We investigated the functional connectivity dynamics in transm
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases TSPO PET imaging is widely used to quantify microglial activation. Here, the authors show that TSPO expression increases in activated rodent but not human microglia, implying that in huma...