Drinking alcohol can cause serious brain damage. Wernicke-Korsakoff syndrome, cerebellar degeneration, and alcoholic dementia are all diseases that can be caused by drinking alcohol. These diseases can cause serious problems with muscle movement, memory, balance, coordination, and thinking. If you drink...
Whetstine for the suggestion to test whether the administration of alcohol to a pregnant female mouse leads to histone acetylation in the gestating fetal brain. G.E. was supported by The Brody Family Medical Trust Fund Fellowship in Incurable Diseases of The Philadelphia Foundation. This work was ...
Alcoholism is a chronic disease, progressive and often turn fatal; it is a disorder and not due to other diseases or emotional problems. Many scientists have tried to pinpoint what Alcoholism is, and what this disease may be stemming from. Some people would dispute that alcoholism is only ...
Furthermore, alcohol consumption was associated with a higher white matter lesion volume. These results suggest subclinical structural changes similar to alcohol-related neurological diseases.doi:10.1016/j.alcohol.2020.11.006Ali Haidar SyaifullahAkihiko Shiino...
Alcohol use disorder (AUD) is a widespread disease leading to the deterioration of cognitive and other functions. Mechanisms by which alcohol affects the brain are not fully elucidated. Splicing constitutes a nuclear process of RNA maturation, which resu
Risk factors for the significant increase of the emergence of delirium include advanced age, preexisting neurocognitive disorders, history of alcohol abuse, severe systemic disease (e.g., sepsis and diseases of the respiratory tract), metabolic abnormalities, inadequate pain management, mechanical ventila...
Additionally, mRNA-based therapies can specifically change which genes are expressed to treat diseases like cancer. In the future, we may discover similar therapies for alcohol and substance use disorder. These treatments could potentially target important signaling pathways linked to addiction, altering ...
Certain lifestyle choices, such as smoking, drug abuse and heavy alcohol consumption, are risk factors for a cerebral aneurysm. Other risk factors of a brain aneurysm include older age, hypertension, arteriosclerosis, certain blood infections and head injury. Symptoms of a Brain Aneurysm Some ...
Furthermore, inflammation is thought to be involved in the development of other psychiatric disorders where alcohol does not play a role.109–111 The origin and mechanisms contributing to systemic inflammation in alcohol dependence as well as in other neuropsychiatric diseases are not yet fully ...
we find that low alcohol drinking (LAD) mice have dramatically higher ventral tegmental area (VTA) dopamine neuron firing and burst activity. Unexpectedly, VTA dopamine neuron activity in high alcohol drinking (HAD) mice does not differ from alcohol naive mice. Optogenetically enhancing VTA dopamine...