giving rise to complex neuronal coactivation patterns that are thought to support perception, cognition, and other mental functions1. Understanding the relationship between structure and function is a fundamental question in neuroscience2. With the development of network science and imaging techniques...
Division of Labor.—Division of labor is the law in the organic world as in the industrial. Animals of the lowest type, such as the amœba, do not have separate organs for respiration, digestion, assimilation, elimination, etc., the one tissue performing all of these functions. But in ...
It is largely assumed that the specificity of these interconnections underlies our ability to perceive and classify objects, our behaviors both learned (such as playing the piano) and intrinsic (such as walking), and our memories—not to mention controlling lower-level functions such as maintaining...
a, Schematic diagram illustrating the scAnnot tool (created withBioRender.com). This hierarchical classification model, based on scANVI, categorizes cells into cell types. The first level of classification groups cells into broad cell types, while the second level further classifies cells into more ...
(a, bottom) Venn diagram showing overlaps of differently regulated genes (expressed in all four cell types) and surrounded by pie charts giving the overall cell-specific number of expressed genes including non-regulated and regulated genes. b UpSet plots of gene sets (left) and corresponding ...
reflects t-test statistic strength. (b) Chord diagram representing the number of significant edges between different large-scale networks. Red bands represent edges with stronger functional connectivity in the deaf compared to hearing control, while blue bands represent edges with weaker functional ...
These genes were selected from GO database40 and their functions on cellular senescence were validated according to published studies. Our GO analysis revealed that among the top 20 senescence or ageing-related biological processes, they are mainly associated with cell adhesion, cell proliferation, res...
However, the degree to which brain function is bound by the underlying wiring diagram remains a complex question that has been only partially answered. Here, we introduce the structural-decoupling index to quantify the coupling strength between structure and function, and we reveal a macroscale ...
Adapted from Dourlen P et al. Acta Neuropathologica. 2019 Aug; 138 (2):221–236. Reprinted with permission from Springer Nature Circular diagram of AD genetic risk factors. From outside to inside: (1) genomic loci in alphabetical order; (2) genes therein; (3) expression profiles of the...
Business and financial integration structure diagram The HTAP capability of TiDB means that multiple points can first deploy TiDB in the OLAP field to solve existing pain points. After you have accumulated enough operational and business experience, you can switch to TiDB at a lower cost and risk...