a, Schematic diagram illustrating the scAnnot tool (created withBioRender.com). This hierarchical classification model, based on scANVI, categorizes cells into cell types. The first level of classification groups cells into broad cell types, while the second level further classifies cells into more ...
Despite the fundamental importance of understanding the brain’s wiring diagram, our knowledge of how neuronal connectivity is rewired by traumatic brain injury remains remarkably incomplete. Here we use cellular resolution whole-brain imaging to generat
The thalamus, hypothalamus, and epithalamus all play significant roles in the brain. One of the thalamus' responsibilities is regulating the body through sleep and wake cycles. The hypothalamus secretes hormones that control multiple functions, such as body temperature, sleep, and th...
Higher associative cortical areas are believed to be the origin of top-down signals that are sent downward to sensory and motor cortices to modulate those lower primary areas; however, higher cortical areas themselves also project to subcortical areas such as the thalamus, hypothalamus and brainstem...
GCbt also sends projections to other brain areas including entorhinal cortex, parabrachial nucleus, and nucleus accumbens (data not shown); CeA also sends projections to parabrachial nucleus, bed nucleus of the stria terminalis and lateral hypothalamus (data not shown). Scale bars, 200 μm. (F-...
Here we used functional magnetic resonance imaging (fMRI) to show that the amygdala and hypothalamus are more strongly activated in men than in women when viewing identical sexual stimuli. -Men and women differ in amygdala response to visual sexual stimuli ...
covering 13 overarching brain areas: isocortex, olfactory areas (OLFs), hippocampal formation (HPF), cortical subplate (CTXsp), striatum (STR), pallidum (PAL), thalamus (TH), hypothalamus (HY), midbrain (MB), pons (P), medulla (MY), cerebellum (CB), and fiber tracts (FT) (Figure ...
The rostral-most prosencephalic (forebrain) vesicle then forms two vesicles that are destined to become the telencephalon (cerebral cortex) and the diencephalon (thalamus, hypothalamus, and other structures). This is followed by a complex, dynamic, sequential, and yet temporally overlapping series of...
of focal brain injury in the acute phase [260,261], analysis of CSF composition has confirmed that B cells can mediate the activation of humoral immunity during stroke [217] and cocluster with the immunoglobulins they produce in the thalamus, which in turn leads to cognitive dysfunction [262]...
The rostral-most prosencephalic (fore- brain) vesicle then forms two vesicles that are destined to become the telencephalon (cerebral cortex) and the diencephalon (thalamus, hypothalamus, and other struc- tures). This is followed by a complex, dynamic, sequential, and yet temporally overlapping ...