The overall prevalence of brain death after cardiac arrest is probably underestimated, due to interference from early withdrawal of life-sustaining treatment in patients with severe hypoxic-ischemic brain injury and due to underreporting, because none of the recommended outcome measures of neurological ...
Brain death, also commonly referred to as death by neurologic criteria, has been considered a legal definition of death for decades. Its determination involves many considerations and subtleties. In this review, we discuss the philosophy and history of b
Cardiac arrest can cause hypoxic–anoxic ischemic brain injury due to signaling cascades that lead to damaged cell membranes and vital cellular organelles, resulting in cell death in the setting of low or no oxygen. Some brain areas are more prone to damage than others, so patients with hypoxic...
Sudden cardiac arrest is a leading cause of death worldwide [1]. Despite advances in cardiopulmonary resuscitation (CPR) methods, including the introduction of the automatic electrical defibrillator (AED) and therapeutic hypothermia [2], [3], only about 10 % of adult out-of-hospital cardiac arre...
Calcium Dependence of Toxic Cell Death: A Final Common Pathway Primary cultures of adult rat hepatocytes were treated in the presence or absence of extracellular calcium with ten different membrane-active toxins. In al... FAX Schanne,AB Kane,EE Young,... - 《Science》 被引量: 3360发表: ...
brain deaththe irreversible cessation of all brain activity for an appropriate observation period, at least 24 hours, so that cardiopulmonary functions must be artificially maintained. A presidential commission in the USA accepted criteria for such a diagnosis, including cessation of all brain functions...
example, extreme cooling—sometimes used on patients with brain injuries or after cardiac arrest—can lead to what looks like a cessation of brain activity. Certain drugs may temporarily suppress breath. Reversible mimics of brain death may be caused by Guillain-Barré syndrome or even snake ...
Ac2-26 Alleviates Brain Injury after Cardiac Arrest and Cardiopulmonary Resuscitation in Rats via the eNOS Pathway Background: Brain injury is the leading cause of death following cardiac arrest (CA) and cardiopulmonary resuscitation (CPR). Ac2-26 and endothelial nitric oxide synthase (eNOS) have ...
funded by the Austrian Science Fund FWF is now set to provide scientific insights into one of these still unsolved mysteries: what goes on in the brain of people who are on the brink of death due to cardiac arrest and have memories of the time when their heart had stopped after ...
Sandroni C, D’Arrigo S, Callaway CW, Cariou A, Dragancea I, Taccone FS, Antonelli M (2016) The rate of brain death and organ donation in patients resuscitated from cardiac arrest: a systematic review and meta-analysis. Intensive Care Med 42(11):1661–1671. doi:10.1007/s00134-016-4549...