此外,基于影像学的空间分辨特性,进一步探讨了PVS扩张与神经炎症及血脑屏障破坏的空间分布关系。 近日,剑桥大学联合浙江大学医学院附属第二医院在Brain杂志在线发表了一篇题为“Perivascular space dysfunction in cerebral small vessel disease is related to neuroinflammation”的研究论文。 该研究系统阐述了脑小血管病(cSV...
Cerebral small vessel disease (SVD) is an interesting cause of stroke. Unlike atherosclerosis and atrial fibrillation, the 2 other most common ischemic stroke etiologies, in patients with SVD, the brain undergoes changes leading to white matter hyperintensities (WMH), lacunes, and cerebral microbleeds...
To investigate whether severity and progression of periventricular and deep white matter lesions (WML) and lacunar infarcts were associated with progression of brain atrophy.Within the SMART-MR study, a prospective cohort on MRI changes in patients with symptomatic atherosclerotic disease, 565 patients ...
Introduction: It is unknown whether different types of small vessel disease (SVD), differentially relate to brain atrophy and if co-occurring Alzheimer's disease pathology affects this relation. Methods: In 725 memory clinic patients with SVD (mean age 67 卤 8 years, 48% female) we compared ...
A novel hereditary small vessel disease of the brain ObjectiveOnly few hereditary ischemic small vessel diseases of the brain (SVDB) have been reported so far. Cerebral autosomal dominant arteriopathy with su... S Verreault,A Joutel,F Riant,... - 《Annals of Neurology》 被引量: 53发表: 200...
Lau, Kui KaiWong, Yuen KwunMak, Henry K. FHui, Edward SScientific ReportsThe effect of the total small vessel disease burden on the structural brain network, Xiaopei, Kui Kai Lau,Yuen Kwun-Wong,Henry K.F.Mak & Adwards S.HuiNature.com/Scientific reports,20...
Contrary to these results, in rodent models of ischemic injury, chronic, physiological concentrations of E2 protected the cortex againstMiddle Cerebral Artery Occlusion(MCAO)-induced damage without effecting CBF (Alkayed et al., 2000; Dubal and Wise, 2001; Rusa et al., 1999). These findings we...
摘要 Cerebral small vessel disease is a neurological disease that affects the brain microvasculature and which is c...展开更多 作者 Ruxue Jia Gemma Solé-Guardia Amanda J.Kiliaan 机构地区 Department of Medical Imaging 出处 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第6期1233-1240,共...
Brain Lesions Caused by Cerebrovascular Disease Strokes can be divided into two very broad groups:hemorrhageandischemia.1Hemorrhagerefers to bleeding inside the skull, either into the brain or into the fluid surrounding the brain. The second major types of stroke are ischemic, a term that refers ...
Over the past several decades, a worldwide demographic transition has led to an increasing number of older adults with chronic neurological conditions. These conditions, which have a profound effect on the cognitive function and physical ability of older adults, also have a long preclinical phase. ...