近日,首都医科大学宣武医院卢洁教授和武力勇教授团队在神经病学领域顶级期刊《Brain》联合发表题为“Atrophy network mapping of clinical subtypes and main symptoms in frontotemporal dementia”的研究论文。该研究首次报道了额颞叶痴呆不同亚型...
My husband of 31 years has brain atrophy after having epilepsy. We still have not gotten a prognosis from any doctors. He is 57 years old and has gone downhill for a year. He just got out of the hospital yesterday. We have home health now. His balance is gone and he has to use ...
Tumors can grow and press on other parts of the brain, potentially causing various symptoms depending on their location and size. Unlike some other types of lesions, tumors are defined by the growth of cells that form a mass. The diagnosis of a brain lesion begins with the health care pract...
Inclusion criteria included a diagnosis of a CM, ISM or SSM type of mastocytosis and the existence of psycho-cognitive symptoms/complaints. The diagnosis of mastocytosis and its subtype was made by trained specialized medical doctors and characterized as either CM, ISM or SSM based on the WHO ...
The brain regions in which grey matter atrophy was independently correlated with delusions, agitation and apathy are similar to areas that have been associated with these symptoms in lesion, epilepsy, and schizophrenia, studies. The study of neurodegenerative disorders such as Alzheimer's disease using...
The pathophysiological cascade of Alzheimer’s disease (AD) is thought to begin decades before the diagnosis of clinical dementia1. Thus, being able to identify people in the preclinical stage of AD is fundamental if we are to develop and offer interventions that could potentially delay or deceler...
Observational data was obtained from the Alzheimer’s Disease Neuroimaging Initiative, in which participants underwent plasma assessment and magnetic resonance imaging. Based on their clinical diagnosis, participants were classified as cognitively unimpaired and cognitively impaired. Linear regressions and linear...
Design, Setting, and Participants In this retrospective cross-sectional study of 9834 polysomnograms, BAI was computed among individuals with previously determined dementia, mild cognitive impairment (MCI), or cognitive symptoms but no diagnosis of MCI or dementia, and among healthy individuals without...
AD1 and AD2 distill the neuroanatomical heterogeneity of Alzheimer’s disease into two distinct imaging patterns: AD1 represents a widespread brain atrophy pattern, while AD2 exhibits a focal atrophy pattern in the medial temporal lobe4. These subtypes, in essence, capture more homogeneous disease ef...
Cellular therapies offer a promising therapeutic strategy for the highly malignant brain tumor, glioblastoma (GBM). However, their clinical translation is limited by the lack of effective target identification and stringent testing in pre-clinical m