Naturally occurring melanomas in dogs as models for non-UV pathways of human melanomas Spontaneously occurring melanomas are frequent in dogs. They appear at the same localizations as in humans, i.e. skin, mucosal sites, nail matrix and eyes... Marc,Gillard,Edouard,... - 《Pigment Cell &...
Discrete tumour variables of mutant and wildtype dogs were compared using Fisher's exact test. The survival rates were calculated with Kaplan-Meier plots. The study population consisted of a total number of 29 dogs. The average age of the dogs was 10.8 years and the sex distribution was ...
This advancement paves the way for further research to define the prognostic and predictive role of this tumour marker in dogs and use IHC to stratify dogs for the treatment with BRAF inhibitors.doi:10.1111/vco.12978Leonore AeschlimannInstitute of Animal PathologyAlexandra Kehl...
Although many human cancers carry the mutated BRAF gene, this mutation has not yet been characterized in canine cancers. As human and canine cancers share molecular abnormalities, we hypothesized that BRAF gene mutations also exist in canine cancers. To test this hypothesis, we sequenced the exon ...
In dogs, the BRAF mutation (V595E) is common in bladder and prostate cancer and represents a specific diagnostic marker. Recent advantages in artificial intelligence (AI) offer new opportunities in the field of tumour marker detection. While AI histology studies have been conducted in humans to ...
The presence of BRAF variant V595E, as well as an increased cyclooxygenase-2 (COX-2) expression in canine transitional cell carcinoma (TCC) are well-described in the literature. The aim of the present study was to investigate the correlation between breed (terrier versus non-terrier dogs), ...
For YTPL, particle size was found to be similar at all the DOGS-NTA-Ni: YSA ratios (Figure 1a). A slight decline in particle size from 109.45 nm to 89.75 nm was observed after incubation with YSA. An increase in the zeta potential of liposomes was observed in a concentration-dependent ...