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All mice used in DS related studies exist on a mixed genetic background, with comparative groups (euploidvs. Brwd1+/–vs. Ts65Dn vs. Ts65Dn;Brwd1+/–) maintained on the same mixed background (DBA/2J x B6EiC3Sn/J) for experimental testing. Briefly, trisomicTs(176)65Dn(Ts65Dn) fe...
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