Our purpose is reimagining energy for people and our planet. We want to help the world reach net zero and improve people’s lives. We want to be an energy company with purpose; one that is trusted by society, valued by shareholders and motivating for eve
The heart is an extraordinarily versatile pump, finely tuned to respond to a multitude of demands. Given the heart pumps without rest for decades its effic
Our 2007 ACG operating expenditure Seven of BP's top 10 producing wells worldwide are in the ACG field - the largest oil field in the Azerbaijan sector of the Caspian basin. BP's Top 10 Producers Chirag A19 Kapok KA04B03 Azeri B09 Kapok KA08B01 Azeri B06 Kapok KA10B01 Azeri B10 ...
On the other hand, the Cuff-Less Blood Pressure Estimation Dataset13 available in the UCI repository (BP-UCI) is a subset generated from the MIMIC-II database created by Kachuee et al.14. This dataset contains 12,000 records of 942 patients, with simultaneous PPG, ABP, and ECG data usin...
Hutchinson–Gilfor progeria syndrome (HGPS) is caused by a mutation in Lamin A resulting in the production of a protein called progerin. The accumulation of progerin induces inflammation, cellular senescence and activation of the P53 pathway. In this stu
Upon signal activation, the TIR domain of Myd88 mediates the interaction with intracellular TIR domains of the TLRs, while DD recruits IRAK4 and IRAK1/2 to form a myddosome complex and activates the NF-κB pathway through the phosphorylation cascade. As the first step in this process, TIR ...
A Rheb-PRKAG2 fusion was reported in a RNA-Seq analyses of 18 types of cancers [170], but it remains largely unknown if this fusion exerts an oncogenic fusion via activating mTORC1. A S6K1-EFCAB3 fusion was reported in FusionGDB, while its function in cancer remains to be determined....
Download: Download full-size image Figure 1. Genetic summary of the reported individuals with homozygous GTPBP1 and GTPBP2 variants (A) Pedigrees of the sixteen families described. Square, male; circle, female; black filled symbol, affected individual; white symbols, unaffected individuals. Double ...
Anderson GR, Semenov A, Song JH, Martemyanov KA (2007a). The membrane anchor R7BP controls the proteolytic stability of the striatal specific RGS protein, RGS9-2. J Biol Chem 282: 4772–4781. Blundell J, Hoang CV, Potts B, Gold SJ, Powell CM (2008). Motor coordination deficits in...
This global event, which started around 4,400 yr BP and ended some 600 years later, has been variously termed the "4000 yr BP Event"43,45, the "4.2 ka event"33,39, and the "Bond Holocene IRD Event 3"26. It was the most significant cold period since the 8.2 ka event, and...